Diagnostic Centre, University Clinic for Development of Innovative Patient Pathways, Silkeborg Regional Hospital, Silkeborg 8600, Denmark.
Department of Clinical Medicine, Aarhus University, Aarhus 8200, Denmark.
Eur Heart J Qual Care Clin Outcomes. 2023 Jun 21;9(4):389-396. doi: 10.1093/ehjqcco/qcac038.
To examine (i) the sex-specific associations between three social determinants of health (SDOH) and use of ablation after incident atrial fibrillation (AF), and (ii) the temporal trends in these associations.
We conducted a nationwide cohort study of patients with an incident hospital diagnosis of AF between 2005 and 2018. SDOH at the time of AF diagnosis included three levels of educational attainment, tertile groups of family income, and whether the patient was living alone. Outcome was catheter ablation for AF. We used cause-specific proportional hazard models to estimate hazard ratios (HR) with 95% CI and adjusted for age. To examine temporal trends, we included an interaction term between the exposure and calendar years. Among 122 276 men, those with lower education [HR 0.49 (95%CI 0.45-0.53)] and 0.72 (0.68-0.77) for lower and medium vs. higher], lower income [HR 0.31 (0.27-0.34) and 0.56 (0.52-0.60) for lower and medium vs. higher], and who lived alone [HR 0.60 (0.55-0.64)] were less likely to receive AF ablation. Among 98 476 women, those with lower education [HR 0.45 (0.40-0.50) and 0.83 (0.75-0.91) for lower and medium vs. higher], lower income [HR 0.34 (0.28-0.40) and 0.51 (0.46-0.58) for lower and medium vs. higher], and who lived alone [HR 0.67 (0.61-0.74)] were less likely to receive AF ablation. We found no evidence of temporal trends in the associations.
In the Danish universal healthcare system, patients with AF who had lower educational attainment, lower family income, or were living alone were less likely to undergo AF ablation.
探讨(i)三种健康社会决定因素(SDOH)与房颤(AF)后消融治疗的性别特异性关联,以及(ii)这些关联的时间趋势。
我们对 2005 年至 2018 年期间患有 AF 首次住院诊断的患者进行了全国性队列研究。AF 诊断时的 SDOH 包括三个教育程度水平、家庭收入 tertiles 组和患者是否独居。结局为房颤导管消融治疗。我们使用特定原因的比例风险模型来估计风险比(HR)及其 95%置信区间,并调整年龄。为了检验时间趋势,我们在暴露因素和日历年度之间纳入了一个交互项。在 12276 名男性中,那些受教育程度较低的人(HR 0.49(95%CI 0.45-0.53))和较低及中等收入的人(HR 0.72(0.68-0.77))相比,收入较高的人,以及独居的人(HR 0.31(0.27-0.34)和 0.56(0.52-0.60))接受 AF 消融治疗的可能性较低。在 98476 名女性中,那些受教育程度较低的人(HR 0.45(0.40-0.50)和 0.83(0.75-0.91))和较低及中等收入的人(HR 0.34(0.28-0.40)和 0.51(0.46-0.58))相比,收入较高的人,以及独居的人(HR 0.67(0.61-0.74))接受 AF 消融治疗的可能性较低。我们没有发现这些关联的时间趋势的证据。
在丹麦全民医疗保健系统中,AF 患者的教育程度较低、家庭收入较低或独居的患者接受 AF 消融治疗的可能性较低。