Department of Neonatology, Children's Hospital, Capital Institute of Pediatrics, Beijing, China.
Department of Neonatology, Children's Hospital, Capital Institute of Pediatrics, Beijing, China.
Pediatr Neonatol. 2022 Sep;63(5):445-451. doi: 10.1016/j.pedneo.2022.03.014. Epub 2022 May 27.
Infectious diseases are the major cause of children's deaths all over the world. With the development of evidence-based medicine, etiological diagnosis becomes more and more important. Since traditional methods have been unable to meet the needs of diagnosis and treatment, metagenomic next-generation sequencing (mNGS) gradually shows its unique advantages for pathogen diagnosis. This article aimed to introduce the application of mNGS technology in the diagnosis and treatment of neonatal and puerile infectious diseases by providing some examples.
传染病是全世界儿童死亡的主要原因。随着循证医学的发展，病因诊断变得越来越重要。由于传统方法已经不能满足诊断和治疗的需要，宏基因组下一代测序（mNGS）逐渐显示出其在病原体诊断方面的独特优势。本文通过举例的方式，介绍 mNGS 技术在新生儿和婴幼儿感染性疾病诊断和治疗中的应用。
