Erasmus MC, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, PO Box 2040, Rotterdam CA 3000, the Netherlands; Erasmus MC, Department of Psychiatry, Section of Medical Psychology and Psychotherapy, PO Box 2040, Rotterdam CA 3000, the Netherlands.
Erasmus MC, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, PO Box 2040, Rotterdam CA 3000, the Netherlands.
Reprod Biomed Online. 2022 Sep;45(3):599-607. doi: 10.1016/j.rbmo.2022.05.001. Epub 2022 May 11.
Polycystic ovary syndrome (PCOS) is a common endocrine disorder with physical and psychological complaints, especially high depression scores. Cognitive behavioural therapy (CBT) is the first-line psychological treatment for depression. The objective of this study was to examine the effect of different types of CBT interventions and the effects on depression scores in women with PCOS. A literature search was performed in six databases up to July 2020. Studies published in English, in which depression scores were compared between groups during a CBT intervention in women with PCOS, were included. A total of 4854 studies were identified, of which eight studies were included in the systematic review and five in the meta-analysis. CBT ranged from 8 to 52 weeks and involved between 8 and 20 sessions. An overall Cohen's d effect size of 1.02 (95% confidence interval 0.02-2.02) was found in favour of CBT compared with standard care. To conclude, most psychological interventions applying CBT are effective in lowering depression scores in women with PCOS. These results should be interpreted with caution due to methodological differences and quality of the studies. More clinical trials are needed to assess how many sessions of CBT are necessary to treat depression in women with PCOS.
多囊卵巢综合征（PCOS）是一种常见的内分泌疾病，伴有身体和心理不适，尤其是抑郁评分较高。认知行为疗法（CBT）是治疗抑郁症的一线心理疗法。本研究旨在探讨不同类型的 CBT 干预措施对 PCOS 女性抑郁评分的影响。我们在六个数据库中进行了文献检索，截至 2020 年 7 月。纳入了在 PCOS 女性中进行 CBT 干预期间比较抑郁评分的、发表于英文期刊的研究。共确定了 4854 项研究，其中 8 项研究进行了系统评价，5 项进行了荟萃分析。CBT 的持续时间为 8 至 52 周，涉及 8 至 20 次治疗。与标准护理相比，CBT 的总体 Cohen's d 效应量为 1.02（95%置信区间 0.02-2.02）。综上所述，大多数应用 CBT 的心理干预措施在降低 PCOS 女性的抑郁评分方面是有效的。由于研究方法和质量的差异，这些结果应谨慎解释。需要更多的临床试验来评估治疗 PCOS 女性抑郁症需要多少次 CBT。
