Kim Ji-Hyun, Yu Hea-Jin
College of Nursing, Sahmyook University, Seoul 01795, Republic of Korea.
J Clin Med. 2024 Jan 11;13(2):412. doi: 10.3390/jcm13020412.
(1) Background: Women in their middle years undergoing perimenopause encounter a range of physical and psychological alterations attributed to hormonal changes. The prominent symptoms among menopausal women are depressive symptoms and sleep-related problems. The aim of this study was to conduct a meta-analysis examining the effects of Cognitive Behavioral Therapy (CBT) on women going through menopause, specifically focusing on depressive symptoms and sleep problems. We analyzed studies conducted both within the country and across international settings over the last decade. (2) Methods: A search of the literature was conducted-a targeted search, exclusively considering randomized controlled trials (RCTs) that were published within the timeframe spanning from 15 June 2013 to 15 June 2023. (3) Findings: Upon reviewing nine studies that satisfied our inclusion criteria and involved a total of 923 participants, it was noted that four of these studies incorporated diverse cognitive-behavioral strategies. Among the nine studies, a total of four were included in the meta-analysis: two measured depressive symptoms, and two measured sleep quality. The combined effect size for depressive symptoms was found to be 3.55 (95% confidence interval: -5.48, -1.61; < 0.05), and for sleep quality, it was 0.78 (95% confidence interval: -1.32, -0.25; = 0.004). (4) Conclusions: Our review emphasizes the necessity for conducting larger-scale studies focused on the application of CBT for women experiencing menopausal symptoms. Additionally, it is recommended to approach the interpretation of these results with caution due to discrepancies in methodology and the overall quality of the studies. Further clinical trials are necessary to establish the ideal number of CBT sessions needed for the effective treatment of depression in menopausal women. Future studies should cover a wider range of geographical locations, including more countries, and focus on various outcomes such as depressive symptoms and sleep quality.
（1）背景：处于围绝经期的中年女性会经历一系列因激素变化引起的身体和心理改变。绝经女性的突出症状是抑郁症状和睡眠相关问题。本研究的目的是进行一项荟萃分析，考察认知行为疗法（CBT）对绝经女性的影响，特别关注抑郁症状和睡眠问题。我们分析了过去十年内在国内和国际开展的研究。（2）方法：进行文献检索——有针对性的检索，仅考虑在2013年6月15日至2023年6月15日期间发表的随机对照试验（RCT）。（3）结果：在审查了9项符合我们纳入标准且共涉及923名参与者的研究后，注意到其中4项研究采用了多种认知行为策略。在这9项研究中，共有4项纳入了荟萃分析：2项测量了抑郁症状，2项测量了睡眠质量。抑郁症状的合并效应量为3.55（95%置信区间：-5.48，-1.61；P<0.05），睡眠质量的合并效应量为0.78（95%置信区间：-1.32，-0.25；P = 0.004）。（4）结论：我们的综述强调了开展更大型研究的必要性，这些研究应聚焦于将CBT应用于有绝经症状的女性。此外，鉴于研究方法和整体质量存在差异，建议谨慎解读这些结果。需要进一步的临床试验来确定有效治疗绝经女性抑郁症所需的CBT疗程的理想数量。未来的研究应涵盖更广泛的地理位置，包括更多国家，并关注各种结果，如抑郁症状和睡眠质量。
