Faculty of Medicine, University of Basel, Basel, Switzerland.
Department of Neurology, Cantonal Hospital, Sankt Gallen, Switzerland.
Brain Behav. 2022 Aug;12(8):e2649. doi: 10.1002/brb3.2649. Epub 2022 Jul 10.
To analyze the increase in diameter of the nerve roots C5 and C6 in early childhood.
The nerve roots of 56 children aged 0 days to 10 years (47 younger than 2 years) were examined by high-resolution ultrasound imaging. The correlation of diameter and age was statistically tested and a logarithmic regression analysis was performed to develop a logarithmic growth model.
The increase in nerve root diameter is greatest during the first 2 years of life and then the growth rate decreases steadily. The relationship between age and diameter follows a logarithmic curve (p < 10 ).
The main increase in the diameter of the nerve roots happens in the first 2 years of life. Comparing data from a previous study, our data also suggest that the maturation of the proximal part of the median nerve is comparable to the maturation of its distal segments. This suggests a synchronous maturation of the axons and myelin sheath for the whole extent of the nerve, from the radix to its very distal part.
Normative values for the size of the cervical nerve roots C5 and C6; an insight into the maturation of the proximal parts of the peripheral nervous system; and the correlation between age and cervical root diameter.
分析儿童早期 C5 和 C6 神经根直径的增加。
使用高分辨率超声成像检查了 56 名 0 天至 10 岁（47 名年龄小于 2 岁）儿童的神经根。对直径与年龄的相关性进行了统计学检验，并进行了对数回归分析，以建立对数生长模型。
神经根直径的增加在生命的头 2 年最大，然后生长速度稳定下降。年龄与直径之间的关系呈对数曲线（p<0.001）。
神经根直径的主要增加发生在生命的头 2 年。与之前的研究数据相比，我们的数据还表明，正中神经近端部分的成熟与其远端部分的成熟相当。这表明从神经根的根部到其最远端，整个神经的轴突和髓鞘同步成熟。
颈神经根 C5 和 C6 大小的正常参考值；对外周神经系统近端部分成熟的深入了解；以及年龄与颈神经根直径的相关性。
