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[外周神经系统发育与成熟的神经生理学]

[Neurophysiology of the development and maturation of the peripheral nervous system].

作者信息

García-García A, Calleja-Fernández J

机构信息

Servicio de Neurofisiología Clínica, Hospital Universitario Marqués de Valdecilla, Santander, España.

出版信息

Rev Neurol. 2004;38(1):79-83.

PMID:14730498
Abstract

INTRODUCTION

Peripheral nerve maturation accounts during fetal life and infancy and varies with age. Nerve conduction studies are an objective procedure to investigate the development of the motor and sensory nerves.

METHOD

We present a review of peripheral nervous system maturation studies in infancy, including our normal control group of infants from 1 week to 6 years of age. Motor and sensory nerve conduction velocity at birth is about one-half that of the normal adults, increases very quickly during the first year of life and reaches adult values between 3 and 5 years of age. All these electrophysiologic changes parallel the increase in numbers of large myelinated fibres throughout infancy.

CONCLUSIONS

Nerve conduction studies are an accurate and non-invasive method of evaluating the peripheral nerve maturation in paediatric population when motor and sensory functions are particularly difficult to assess clinically.

摘要

引言

胎儿期和婴儿期外周神经成熟情况各异且随年龄变化。神经传导研究是一种用于研究运动和感觉神经发育的客观方法。

方法

我们对婴儿期外周神经系统成熟研究进行了综述,包括我们从1周龄至6岁的正常婴儿对照组。出生时运动和感觉神经传导速度约为正常成年人的一半,在生命的第一年增长非常迅速,并在3至5岁时达到成人水平。所有这些电生理变化与整个婴儿期有髓大纤维数量的增加相一致。

结论

当运动和感觉功能在临床上特别难以评估时,神经传导研究是评估儿科人群外周神经成熟的一种准确且非侵入性的方法。

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