School of Health, Federal University of Rio Grande do Norte, Natal, Brazil.
Department of Nursing, Federal University of Mato Grosso do Sul, Campo Grande, Brazil.
Transplant Proc. 2022 Jun;54(5):1190-1196. doi: 10.1016/j.transproceed.2022.03.030. Epub 2022 Jul 8.
The process of capturing and classifying the viability of corneal tissue for corneal transplantation is complex. The biomicroscopic examination is one of the techniques used to evaluate the quality of corneal tissues. The aim of this study was to analyze the relationship between the evaluation criteria used in biomicroscopic examination using a slit lamp and the classification of the quality of corneal tissue.
This is a longitudinal, retrospective cohort study, performed at the Human Ocular Tissue Bank in the state of Rio Grande do Norte, Brazil. The sample consisted of 419 corneas donated between 2005 to 2016.
After the evaluation, the 419 corneas were classified as excellent (8 -1.91%), good (217 - 51.79%), regular (85 - 20.29%), and bad (109 - 26.01%). The classification of corneal quality attributed by ophthalmologists considered 13 criteria: senile arch, scars, epithelial defect, epithelial exposure, stromal infiltrate, subepithelial opacity, pterygium, Descemet's folds, stromal edema, stromal streak, cornea guttata, specular reflex, and cell loss endothelial. The quality of the cornea classified as excellent and good showed a statistically significant association (P value < .05) with senile arch, scar, epithelial defect, epithelial exposure, Descemet's folds, stromal edema, stromal streak, cornea guttata, specular reflex, and losses of endothelial cells; they had evaluated criteria that were absent or slightly present.
The evaluation of the corneal quality for corneal transplantation should involve the implementation of reliable techniques and trained, qualified professionals. There is a need to create evaluation instruments that consider the criteria according to their degree of interference in the quality of corneal tissue.
获取和分类角膜组织活力以用于角膜移植的过程十分复杂。生物显微镜检查是评估角膜组织质量的技术之一。本研究旨在分析使用裂隙灯进行生物显微镜检查时使用的评估标准与角膜组织质量分类之间的关系。
这是一项在巴西北里奥格兰德州人类眼组织库进行的纵向回顾性队列研究。该样本由 2005 年至 2016 年期间捐赠的 419 个角膜组成。
经过评估，419 个角膜被分类为优秀（8-1.91%）、良好（217-51.79%）、一般（85-20.29%）和差（109-26.01%）。眼科医生进行的角膜质量分类考虑了 13 个标准：老年弓、瘢痕、上皮缺损、上皮暴露、基质浸润、上皮下混浊、翼状胬肉、角膜后弹力层褶皱、基质水肿、基质条纹、角膜细点状混浊、镜面反射和内皮细胞丢失。被分类为优秀和良好的角膜质量与老年弓、瘢痕、上皮缺损、上皮暴露、角膜后弹力层褶皱、基质水肿、基质条纹、角膜细点状混浊、镜面反射和内皮细胞丢失呈显著相关（P 值<.05）；这些标准表现为缺失或轻微存在。
角膜移植的角膜质量评估应涉及实施可靠的技术和经过培训的合格专业人员。需要创建评估工具，根据其对角膜组织质量的干扰程度考虑标准。
