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[供体角膜质量与供体年龄及死亡原因的关系评估]

[Evaluation of the quality of donor corneas in relation to the age of donor and cause of death].

作者信息

Pantaleão Gleisson Rezende, Zapparolli Márcio, Guedes Guilherme Barroso, Dimartini Junior Wilson Moreira, Vidal Cristiane Carvalho, Wasilewski Daniel, Moreira Hamilton

机构信息

Banco de Tecidos Oculares, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brasil.

出版信息

Arq Bras Oftalmol. 2009 Sep-Oct;72(5):631-5. doi: 10.1590/s0004-27492009000500006.

DOI:10.1590/s0004-27492009000500006
PMID:20027399
Abstract

PURPOSE

To analyze the quality of the corneas evaluated by slit lamp examination in the Eye Bank of the Hospital de Clínicas UFPR and its relation to donor age and cause of death.

METHODS

Analysis of 492 corneas, evaluated in BTO HC-UFPR between August 2006 to August 2008. Each cornea was classified regarding the quality as: very good, good, regular and bad; and according to clarity, epithelial defect, stromal edema, Descemet's folds, stromal opacity, corneal scarring, endothelial density and guttata.

RESULTS

The mean donor age was 42.74 years (sd=17.77 years). Among the causes of death, trauma was the most common with 46.18%, followed by cardiovascular causes with 41.86%. In relation to the cornea, 57.11% were classified as 'good', followed by 20.73% as 'regular', 16.87% as 'very good' and 5.28% as 'bad'. With the application of statistical tests based on ordinal regression model, trauma deaths corneas tend to be better, as well as those of younger patients.

CONCLUSIONS

Statistically, the corneas from younger donors tend to have better graduations in the assessment, as well as the corneas from donors dead by trauma that tend to have better quality when compared to corneas from donors dead by cardiovascular and other systemic diseases.

摘要

目的

分析巴拉那联邦大学临床医院眼库通过裂隙灯检查评估的角膜质量及其与供体年龄和死亡原因的关系。

方法

对2006年8月至2008年8月在巴拉那联邦大学临床医院眼库评估的492只角膜进行分析。每只角膜根据质量分类为:非常好、好、一般和差;并根据清晰度、上皮缺损、基质水肿、后弹力层褶皱、基质混浊、角膜瘢痕、内皮细胞密度和角膜小滴进行分类。

结果

供体平均年龄为42.74岁(标准差=17.77岁)。在死亡原因中,创伤最为常见,占46.18%,其次是心血管原因,占41.86%。关于角膜,57.11%被分类为“好”,其次是20.73%为“一般”,16.87%为“非常好”,5.28%为“差”。通过基于有序回归模型的统计检验应用,创伤死亡供体的角膜往往更好,年轻患者的角膜也是如此。

结论

从统计学上看,年轻供体的角膜在评估中往往有更好的分级,与死于心血管和其他系统性疾病的供体的角膜相比,死于创伤的供体的角膜质量往往更好。

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