Gao Lan, Tan Elise, Kim Joosup, Bladin Christopher F, Dewey Helen M, Bagot Kathleen L, Cadilhac Dominique A, Moodie Marj
Deakin Health Economics, Institute for Health Transformation, Deakin University, Geelong, VIC, Australia.
Stroke and Ageing Research, School of Clinical Sciences at Monash Health, Monash University, Melbourne, VIC, Australia.
Front Neurol. 2022 Jun 20;12:804355. doi: 10.3389/fneur.2021.804355. eCollection 2021.
Few countries have established national programs to maximize access and reduce operational overheads. We aimed to use patient-level data up to 12 months to model the potential long-term costs and health benefits attributable to implementing such a program for Australia.
A Markov model was created for Australia with an inception population of 10,000 people with stroke presenting to non-urban or suburban hospitals without stroke medical specialists that could receive stroke telemedicine under a national program. Seven Markov states represented the seven modified Rankin Scale (mRS) scores (0 no disability to 6 dead) plus an absorbing state for all other causes of death. The literature informed inputs for the model; for the telemedicine program (including program costs and effectiveness) and patients, these were extrapolated from the Victorian Stroke Telemedicine (VST) program with the initial status of patients being their health state at day 365 as determined by their mRS score. Costs (2018 Australian dollars, healthcare, non-medical, and nursing home) and benefits were reported for both the societal and healthcare perspectives for up to a 25 years (lifetime) time horizon.
We assumed 4,997 to 12,578 ischemic strokes would arrive within 4.5 h of symptom onset at regional hospitals in 2018. The average per person lifetime costs were $126,461 and $127,987 from a societal perspective or $76,680 and $75,901 from a healthcare system perspective and benefits were 4.43 quality-adjusted life years (QALYs) and 3.98 QALYs gained, respectively, for the stroke telemedicine program and practice without such program. The stroke telemedicine program was associated with a cost saving of $1,526 (from the societal perspective) or an additional $779 (from the healthcare system perspective) and an additional 0.45 QALY gained per patient over the lifetime. The incremental costs of the stroke telemedicine program ($2,959) and management poststroke ($813) were offset by cost savings from rehospitalization (-$552), nursing home care (-$2178), and non-medical resource use (-$128).
The findings from this long-term model provide evidence to support ongoing funding for stroke telemedicine services in Australia. Our estimates are conservative since other benefits of the service outside the use of intravenous thrombolysis were not included.
很少有国家制定全国性计划以最大限度地扩大医疗服务可及性并降低运营成本。我们旨在利用长达12个月的患者层面数据,对澳大利亚实施此类计划可能产生的长期成本和健康效益进行建模。
为澳大利亚创建了一个马尔可夫模型,初始人群为10000名中风患者,他们前往没有中风医学专家的非城市或郊区医院就诊,这些医院可在全国性计划下接受中风远程医疗服务。七个马尔可夫状态代表七个改良Rankin量表(mRS)评分(0分表示无残疾至6分表示死亡),再加上一个所有其他死因的吸收状态。模型的输入数据来源于文献;对于远程医疗计划(包括计划成本和效果)以及患者,这些数据是根据维多利亚中风远程医疗(VST)计划推断得出的,患者的初始状态为其在第365天根据mRS评分确定的健康状态。报告了长达25年(终身)时间范围内社会和医疗保健视角下的成本(2018澳元,包括医疗保健、非医疗和疗养院费用)和效益。
我们假设2018年在地区医院有4997至12578例缺血性中风患者在症状发作后4.5小时内到达。从社会角度看,每人终身平均成本为126461澳元和127987澳元,从医疗系统角度看为76680澳元和75901澳元,中风远程医疗计划和无此类计划的实践分别获得的效益为4.43个质量调整生命年(QALY)和3.98个QALY。中风远程医疗计划在终身期间每位患者节省成本1526澳元(从社会角度)或额外节省779澳元(从医疗系统角度),并额外获得0.45个QALY。中风远程医疗计划(2959澳元)和中风后管理(813澳元)的增量成本被再住院(-552澳元)、疗养院护理(-2178澳元)和非医疗资源使用(-128澳元)节省的成本所抵消。
这个长期模型的研究结果为澳大利亚中风远程医疗服务的持续资金支持提供了证据。由于未包括静脉溶栓治疗之外该服务的其他效益,我们的估计较为保守。