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血液透析患者的医源性感染性心内膜炎:一例病例报告及文献综述

Iatrogenic Infective Endocarditis in Hemodialysis Patients: A Case Report and Review of the Literature.

作者信息

Oullaï Ali, Cubilier Edouard, Salaouatchi Mohamed Tayeb, Taghavi Maxime, Zouggari Yasmin, Nortier Joëlle, Mesquita Maria Do Carmo Filomena

机构信息

Department of Nephrology, Brugmann University Hospital, Université Libre de Bruxelles, Brussels, Belgium.

出版信息

Case Rep Nephrol. 2022 Jun 29;2022:8500299. doi: 10.1155/2022/8500299. eCollection 2022.

Abstract

Foreign bodies such as implanted cardiac devices are susceptible to infections and may be involved in infective endocarditis. Exposure to pathogens, by frequent use of intravascular accesses for hemodialysis (i.e., catheters or fistulas), combined with high rates of degenerative heart valve diseases in hemodialysis patients, both favor the development of infective endocarditis in this population. The mitral and aortic valves are predominantly implicated in endocardial infections. The involvement of both mitral and tricuspid valves is rare in the general population but can occur in hemodialysis patients with implanted cardiac devices. Infective endocarditis is associated with high morbidity and mortality rates among hemodialysis patients, mostly because of the complications of septic emboli. Prevention, prophylaxis, and early diagnosis of endocarditis can be lifesaving in this fragile population. We report a case of right and left heart methicillin-sensitive endocarditis with cerebral septic emboli in an elderly hemodialysis patient carrier of an arteriovenous fistula and an ipsilateral nonleadless pacemaker.

摘要

诸如植入式心脏装置等异物易受感染,可能会引发感染性心内膜炎。通过频繁使用血管通路进行血液透析(即导管或瘘管)接触病原体,再加上血液透析患者中退行性心脏瓣膜疾病的高发病率,这两者都有利于该人群感染性心内膜炎的发生。二尖瓣和主动脉瓣主要与心内膜感染有关。二尖瓣和三尖瓣同时受累在普通人群中很少见,但在植入心脏装置的血液透析患者中可能发生。感染性心内膜炎在血液透析患者中与高发病率和死亡率相关,主要是因为脓毒性栓子的并发症。心内膜炎的预防、预防用药和早期诊断对这个脆弱人群来说可能是救命的。我们报告一例老年血液透析患者,该患者患有动静脉瘘和同侧无导线起搏器,发生了伴有脑脓毒性栓子的右心和左心甲氧西林敏感的心内膜炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/310b/9259234/0647d9f65bc8/CRIN2022-8500299.001.jpg

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