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胆管内乳头状肿瘤的外科治疗:两例报告并文献复习

Surgical Treatment of Intraductal Papillary Neoplasm of the Bile Duct: A Report of Two Cases and Review of the Literature.

作者信息

Li Binjie, Liu Zhiqiang, Meng Zhuo, Li Mingyang, Tian Weijun, Liu Quanyan

机构信息

Department of Hepatobiliary Surgery, Tianjin Medical University General Hospital, Tianjin, China.

出版信息

Front Oncol. 2022 Jun 23;12:916457. doi: 10.3389/fonc.2022.916457. eCollection 2022.

DOI:10.3389/fonc.2022.916457
PMID:35814451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9259795/
Abstract

Intraductal papillary neoplasm of the bile duct (IPNB) is a rare bile duct tumor characterized by intraductal papillary or villous neoplasms covered by neoplastic epithelium with fine fibrovascular stalks in the dilated bile ducts (1). Its true etiology remains unknown. Herein, we report two cases of IPNB that underwent surgical resection. The first case was a 66-year-old male who complained of upper abdominal pain for three years. We found obstruction of the common bile duct and dilation of the intrahepatic and extrahepatic bile ducts after MRCP. Laparoscopic hepatic segmentectomy (S2, S3, S4), resection of the common bile duct, cholecystectomy, and hepaticojejunostomy were performed. The second case was a 67-year-old male with asymptomatic dilation of the intrahepatic duct. The patient underwent robot-assisted laparoscopic hepatic segmentectomy (S5, S6, S7, S8), resection of the common bile duct, hepaticojejunostomy and cholecystectomy.

摘要

胆管内乳头状肿瘤(IPNB)是一种罕见的胆管肿瘤,其特征为扩张胆管内被肿瘤上皮覆盖的具有纤细纤维血管蒂的乳头状或绒毛状肿瘤(1)。其确切病因尚不清楚。在此,我们报告两例接受手术切除的IPNB病例。第一例是一名66岁男性,主诉上腹部疼痛三年。经磁共振胰胆管造影(MRCP)检查后,我们发现胆总管梗阻以及肝内和肝外胆管扩张。遂行腹腔镜肝段切除术(S2、S3、S4)、胆总管切除术、胆囊切除术和肝空肠吻合术。第二例是一名67岁男性,有肝内胆管无症状扩张。患者接受了机器人辅助腹腔镜肝段切除术(S5、S6、S7、S8)、胆总管切除术、肝空肠吻合术和胆囊切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fea7/9259795/bf79d90c62ad/fonc-12-916457-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fea7/9259795/805830cf0f10/fonc-12-916457-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fea7/9259795/bf79d90c62ad/fonc-12-916457-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fea7/9259795/805830cf0f10/fonc-12-916457-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fea7/9259795/bf79d90c62ad/fonc-12-916457-g002.jpg

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本文引用的文献

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Front Med (Lausanne). 2021 Sep 16;8:675720. doi: 10.3389/fmed.2021.675720. eCollection 2021.
2
A case of intraductal papillary neoplasm of the bile duct accompanied by intraductal papillary mucinous neoplasm of the pancreas and hepatocellular carcinoma.胆管内乳头状肿瘤伴胰腺内胆管乳头状黏液性肿瘤和肝细胞癌 1 例。
Clin J Gastroenterol. 2021 Oct;14(5):1536-1543. doi: 10.1007/s12328-021-01461-z. Epub 2021 Jun 9.
3
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Cureus. 2021 Feb 1;13(2):e13063. doi: 10.7759/cureus.13063.
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Intrahepatic intraductal papillary cystic neoplasm of the bile duct: A case report.肝内胆管内乳头状囊性肿瘤:一例报告。
Ann Med Surg (Lond). 2021 Feb 12;63:102167. doi: 10.1016/j.amsu.2021.02.013. eCollection 2021 Mar.
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