Graduate School of Tianjin University of Traditional Chinese Medicine, No.10 Poyang Lake Road, Tuanbo Xincheng West District, Jinghai District, Tianjin, China.
Comput Intell Neurosci. 2022 Jun 30;2022:9749606. doi: 10.1155/2022/9749606. eCollection 2022.
The main contribution of this research paper is to summarize the results of Meta-analysis of moxibustion in the treatment of infantile diarrhea which is one the common disease and requires considerable attention from the research community and funding organizations. In order to verify that the proposed scheme has merits, a comprehensive searching methodology was adopted by considering various databases such as China Biomedical Literature Database (CBM), China National Knowledge Network Infrastructure (CNKI), Wanfang Database, Pub Med Database, Google Academic, and Cochrane Library. It is important to note that a powerful computer has been utilized to carry out this searching. Finally, only those literature contents are selected which meet the inclusion criteria. Likewise, exclusion criteria was used to exclude irrelevant contents of the literature. RevMan 5.3 was used to analyze the collected data and after reading the titles and abstracts, 29 well-designed studies were selected. Through searching the full text, reading literature, and quality evaluation, 17 papers were finally included. Response rates were reported in all 17 studies, and subgroup analysis was performed based on whether or not other therapies were combined. 7 studies compared the effectiveness of simple moxibustion and conventional therapy in the treatment of infantile diarrhea, and the results showed statistically significant differences [OR = 4.01, 95% CI (2.03, 7.84), < 0.0001]; 10 studies compared the effectiveness of moxibustion combined with other therapies and conventional therapies in the treatment of diarrhea in children, and the results showed that the difference had general meaning [OR = 4.45, 95% CI (2.83, 7.10), < 0.00001]. The funnel plot (in Figure) showed that the distribution of included studies was asymmetrical on both sides of the baseline, which could be considered as publication bias. Traditional Chinese medicine moxibustion could effectively relieve the symptoms of infantile diarrhea, and the effect was significant.
本文的主要贡献在于总结了艾灸治疗小儿腹泻的荟萃分析结果，小儿腹泻是一种常见疾病，需要研究界和资助机构的高度关注。为了验证所提出方案的优点，采用了全面的搜索方法，考虑了中国生物医学文献数据库（CBM）、中国国家知识基础设施（CNKI）、万方数据库、PubMed 数据库、谷歌学术和 Cochrane 图书馆等多个数据库。值得注意的是，使用了一台强大的计算机来进行此搜索。最后，仅选择符合纳入标准的文献内容。同样，使用排除标准排除文献的不相关内容。使用 RevMan 5.3 分析收集的数据，在阅读标题和摘要后，选择了 29 项精心设计的研究。通过搜索全文、阅读文献和质量评估，最终纳入了 17 篇论文。所有 17 项研究均报告了反应率，并根据是否联合其他治疗进行了亚组分析。7 项研究比较了单纯艾灸和常规疗法治疗小儿腹泻的疗效，结果显示差异有统计学意义[OR=4.01，95%CI（2.03，7.84）， < 0.0001]；10 项研究比较了艾灸联合其他疗法与常规疗法治疗小儿腹泻的疗效，结果显示差异具有一般意义[OR=4.45，95%CI（2.83，7.10）， < 0.00001]。漏斗图（如图）显示，纳入研究的分布在基线两侧不对称，可能存在发表偏倚。中医艾灸能有效缓解小儿腹泻症状，疗效显著。
