Torulopsis glabrata osteomyelitis. A case report.

Skeletal infection involving Torulopsis glabrata is extremely rare. A 66-year-old woman developed Torulopsis glabrata osteomyelitis during a course of prolonged antibiotic therapy for staphylococcal pneumonia that occurred as a postoperative complication of a total knee arthroplasty for osteoarthritis. Roentgenograms and a biopsy sample revealed a destructive inflammatory lesion of the vertebrae. The presence of the yeast organism in the lesion was demonstrated definitively by culture and tissue pathology, removing any doubt about the pathogenicity of the organism. The disease was successfully treated with 5-fluorocytosine, and the patient recovered without functional impairments.