Curran M P, Lenke L G
Division of Orthopedic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Spine (Phila Pa 1976). 1996 Apr 1;21(7):866-70. doi: 10.1097/00007632-199604010-00019.
A case report and literature review of the five previous case reports.
To outline the features of Torulopsis glabrata spinal osteomyelitis, including its risk factors, diagnosis, and recommended treatments.
Fungal infections in general and Torulopsis glabrata in particular are becoming increasingly prevalent. Involvement of the spine will likely be more common in the future.
The literature was exhaustively reviewed and the five previous reported cases of Torulopsis glabrata identified and evaluated. This case report is analyzed in the context of the previous five cases.
All patients responded to treatment, which varied from medical alone to medical with operative debridement and spinal fusion.
Various risk factors that predisposed patients to Torulopsis glabrata osteomyelitis were present in all known cases. Diagnosis should rely on examination, history, and radiographic and laboratory evaluations. Medical therapy should be the initial treatment in most cases; however, operative intervention may be needed in patients who do not respond appropriately.
一份病例报告及对之前五例病例报告的文献综述。
概述光滑念珠菌性脊椎骨髓炎的特征，包括其危险因素、诊断及推荐治疗方法。
真菌感染总体上，尤其是光滑念珠菌感染正变得越来越普遍。脊椎受累在未来可能会更常见。
对文献进行了详尽的综述，确定并评估了之前报道的五例光滑念珠菌病例。本病例报告在之前五例病例的背景下进行分析。
所有患者对治疗均有反应，治疗方法从单纯药物治疗到药物治疗联合手术清创及脊柱融合不等。
在所有已知病例中均存在使患者易患光滑念珠菌性骨髓炎的各种危险因素。诊断应依靠检查、病史以及影像学和实验室评估。在大多数情况下，药物治疗应作为初始治疗；然而，对治疗无适当反应的患者可能需要手术干预。
