Instituto de Química de San Luis (INQUISAL-CONICET-UNSL), Laboratorio de Espectrometría de Masas, Bloque III, Ejército de los Andes 950, San Luis, CP5700, Argentina.
Facultad de Ingeniería y Ciencias Agropecuarias, Universidad Nacional de San Luis, Ruta 148 Ext. Norte, Villa Mercedes, CP5730, Argentina.
Anal Methods. 2022 Jul 29;14(29):2841-2848. doi: 10.1039/d2ay00819j.
The retention behavior of a dangerous toxin, ochratoxin A (OTA), present in food samples and derivatives was evaluated using Layered Double Hydroxides (LDHs). This nanomaterial composed mostly of zinc and aluminum was synthesized by the co-precipitation method and the obtained solid was characterized by different techniques, such as XRD, FTIR, TGA, SEM, and N adsorption-desorption isotherms. Experimental conditions were optimized by chemometric tools. Ochratoxin A determination was performed using an ultra-high-performance liquid chromatography (UHPLC) system coupled to tandem mass spectrometry. From the findings, quantitative removal of the mycotoxin was achieved. Thus, a novel, nanostructured, innocuous, low-cost, easily synthesized material, such as the Zn-Al layered double hydroxide, is proposed for ochratoxin A removal. This might represent an effective and sustainable approach with potential applications to different types of food and feed samples.
采用层状双氢氧化物（LDHs）评估了食品样品及其衍生物中存在的一种危险毒素——赭曲霉毒素 A（OTA）的保留行为。这种主要由锌和铝组成的纳米材料是通过共沉淀法合成的，并用不同的技术对得到的固体进行了表征，如 XRD、FTIR、TGA、SEM 和 N 吸附-解吸等温线。实验条件通过化学计量工具进行了优化。采用超高效液相色谱（UHPLC）系统与串联质谱联用的方法对赭曲霉毒素 A 进行了测定。结果表明，该方法可以定量去除真菌毒素。因此，提出了一种新型的、纳米结构的、无毒的、低成本的、易于合成的材料，如 Zn-Al 层状双氢氧化物，用于去除赭曲霉毒素 A。这可能是一种有效且可持续的方法，具有应用于不同类型的食品和饲料样品的潜力。
