Varela-Tapia Clara Lilia, Contreras-Del Carmen Nallely, Hernández-Amaro Hermelinda, Domínguez-Paredes Ana Luisa, Martínez-Barro Daniel
Instituto Mexicano del Seguro Social, Unidad Médica de Alta Especialidad Traumatología, Ortopedia y Rehabilitación, "Dr. Victorio de la Fuente Narváez", Unidad de Medicina Física y Rehabilitación Norte, Servicio de Rehabilitación Cardiopulmonar. Ciudad de México, México.
Instituto Mexicano del Seguro Social, Unidad Médica de Alta Especialidad Traumatología, Ortopedia y Rehabilitación, "Dr. Victorio de la Fuente Narváez", Unidad de Medicina Física y Rehabilitación Norte, Servicio de Medicina Física y Rehabilitación. Ciudad de México, México.
Rev Med Inst Mex Seguro Soc. 2022 Jul 4;60(4):395-401.
COVID-19 predominantly affects the respiratory system. However, persistent extrapulmonary (musculoskeletal and cardiovascular) conditions have been reported.
To determine the most frequent cardiorespiratory and neuromusculoskeletal symptoms in patients with post-acute COVID 19 in a rehabilitation center.
An observational, cross-sectional, descriptive and analytical study of post-acute COVID-19 patients was carried out. Clinical-demographic data, cardiorespiratory and neuromusculoskeletal symptoms were collected upon admission to the cardiopulmonary rehabilitation program. Descriptive statistics and association tests were used through the Chi squared test, taking p < 0.05 as significant.
262 files were collected. The age was 49.9 ± 11.5 years. There was a predominance of males (69.8%). The most prevalent symptoms, in the different degrees of severity (mild, moderate, severe and critical, respectively) were MRC 3 dyspnea (30.4%, 56.8%, 43.1% and 42.9%), weakness (60.9%, 59.5%, 56.9 % and 87.8%), and paresthesias (65.2%, 56.8%, 49.7% and 75.5%). SARS-CoV-2 critical infection was associated with a higher presentation of weakness (p < 0.01), paresthesias (p = 0.01), and dependency in activities of daily living (p < 0.01).
The most frequent cardiorespiratory and neuromusculoskeletal symptoms in patients with post-acute COVID were dyspnea and paresthesias. Critical infection by SARS-CoV-2 was associated with a greater presentation of weakness, paresthesias and dependence on activities of daily living.
新型冠状病毒肺炎（COVID-19）主要影响呼吸系统。然而，已有报告称存在持续的肺外（肌肉骨骼和心血管）病症。
确定康复中心中急性COVID-19后患者最常见的心肺和神经肌肉骨骼症状。
对急性COVID-19后患者进行了一项观察性、横断面、描述性和分析性研究。在患者进入心肺康复项目时收集临床人口统计学数据、心肺和神经肌肉骨骼症状。通过卡方检验进行描述性统计和关联测试，以p<0.05为有统计学意义。
收集了262份病历。年龄为49.9±11.5岁。男性占主导（69.8%）。在不同严重程度（分别为轻度、中度、重度和危重度）下，最常见的症状分别是医学研究委员会（MRC）3级呼吸困难（30.4%、56.8%、43.1%和42.9%）、虚弱（60.9%、59.5%、56.9%和87.8%）以及感觉异常（65.2%、56.8%、49.7%和75.5%）。严重急性呼吸综合征冠状病毒2（SARS-CoV-2）危重症感染与更高比例的虚弱（p<0.01）、感觉异常（p=0.01）以及日常生活活动依赖（p<0.01）相关。
急性COVID后患者最常见的心肺和神经肌肉骨骼症状是呼吸困难和感觉异常。SARS-CoV-2危重症感染与更严重的虚弱、感觉异常以及对日常生活活动的依赖相关。
