Earnshaw J J, Gregson R H, Lowe J S, Hopkinson B R, Makin G S
Clin Radiol. 1987 May;38(3):321-3. doi: 10.1016/s0009-9260(87)80085-5.
There has been a recent increase in the use of low dose intra-arterial streptokinase infusion for the management of patients with acute peripheral arterial occlusions. Though serious complications using this technique occur less frequently than when using systemic thrombolytic therapy, a case is reported where the catheter used to infuse streptokinase perforated the popliteal artery 36 hours after the infusion commenced. The use of softer arterial catheters and restriction of patient movement where possible may prevent the recurrence of this previously unreported hazard.
最近，低剂量动脉内输注链激酶用于治疗急性外周动脉闭塞患者的情况有所增加。尽管使用该技术发生严重并发症的频率低于全身溶栓治疗，但有一例报告称，用于输注链激酶的导管在开始输注36小时后导致腘动脉穿孔。使用更柔软的动脉导管并尽可能限制患者活动，可能会预防这种此前未报告过的风险再次发生。
