Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.
Headache Centre, Pain Management and Neuromodulation Centre, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
World Neurosurg. 2022 Oct;166:159-167. doi: 10.1016/j.wneu.2022.07.014. Epub 2022 Jul 8.
Microscopic microvascular decompression (MVD) of the trigeminal nerve is the gold standard surgical treatment for medically refractory classical trigeminal neuralgia. Endoscopy has significantly advanced surgery and provides enhanced visualization of the cerebellopontine angle and its critical neurovascular structures. We present our initial experience of fully endoscopic microvascular decompression (e-MVD).
This retrospective case series investigated e-MVD performed from September 2016 to February 2020 at a single institution. Clinical data including presenting symptoms, medications, operative findings, postoperative complications, and outcomes were recorded. The 5-point Barrow Neurological Institute (BNI) pain intensity score was used to quantify patients' pain relief.
During the study period, 25 patients with trigeminal neuralgia (10 males, 15 females; mean [SD] age = 63 [10.4] years) underwent e-MVD. All patients had a preoperative BNI score of V. The left side was affected in 15 patients. Complications occurred in 2 patients: both experienced hearing loss, and one experienced transient facial weakness 7 days after surgery. The facial weakness had resolved by the last follow-up. All patients were completely pain-free (BNI score I) immediately postoperatively. On latest follow-up, 22 patients have remained pain-free, and 3 patients have recurrent pain that is being controlled with medication (BNI score III).
Our study demonstrated that e-MVD is a safe, possibly effective method of performing MVD with the added benefit of improved visualization of the operative field for the operating surgeon and the surgical team. Larger prospective studies are required to evaluate whether performing e-MVD confers any additional benefits in long-term clinical outcome of patients with trigeminal neuralgia.
神经微血管减压术(MVD)是治疗药物难治性典型三叉神经痛的金标准手术。内窥镜技术显著提高了手术水平,为桥小脑角及其关键神经血管结构提供了更好的可视化效果。我们报告了我们在单一机构进行的全内窥镜微血管减压术(e-MVD)的初步经验。
这项回顾性病例系列研究调查了 2016 年 9 月至 2020 年 2 月期间在单一机构进行的 e-MVD。记录了包括发病症状、药物治疗、手术发现、术后并发症和结果在内的临床数据。巴罗神经学研究所(BNI)疼痛强度评分用于量化患者的疼痛缓解程度。
在研究期间,25 例三叉神经痛患者(10 名男性,15 名女性;平均[标准差]年龄=63[10.4]岁)接受了 e-MVD。所有患者术前 BNI 评分为 V 级。15 例患者左侧受累。2 例患者发生并发症:均出现听力损失,1 例术后 7 天出现短暂性面瘫。最后一次随访时,面瘫已恢复。所有患者术后即刻完全无痛(BNI 评分为 I 级)。最新随访时,22 例患者仍无痛,3 例患者疼痛复发,用药物控制(BNI 评分为 III 级)。
我们的研究表明,e-MVD 是一种安全、可能有效的 MVD 手术方法,其额外的优点是为手术医生和手术团队提供了手术视野的改善可视化效果。需要更大规模的前瞻性研究来评估 e-MVD 是否会在三叉神经痛患者的长期临床结果中带来任何额外的益处。