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病例报告:百岁老人三叉神经痛的内镜下微血管减压术:一项具有5年随访的标志性病例

Case Report: endoscopic microvascular decompression for trigeminal neuralgia in a centenarian: a landmark case with 5-year follow-up.

作者信息

Fang Xuhao, Tang Feng, Deng Yao, Zhou Yue, Gu Weidong, Mao Renling

机构信息

Department of Neurosurgery, Huadong Hospital, Fudan University, Shanghai, China.

Department of Anesthesiology, Huadong Hospital, Fudan University, Shanghai, China.

出版信息

Front Surg. 2025 Aug 11;12:1537318. doi: 10.3389/fsurg.2025.1537318. eCollection 2025.

Abstract

BACKGROUND

Endoscopic Microvascular Decompression (E-MVD) is a well-established effective treatment option for trigeminal neuralgia (TN). However, its application in ultra-elderly patients, particularly centenarians, has never been documented.

CASE DESCRIPTION

A centenarian with TN for five years presented to our hospital in January 2020. Her symptoms had progressively worsened over the preceding three months. Despite extreme age, her organ function remained relatively preserved based on comprehensive physical and laboratory examinations. E-MVD was performed, and the patient experienced immediate pain relief without any neurological dysfunction. During five years of follow-up, there was no recurrence of symptoms; the patient remains symptom-free at 105 years of age.

CONCLUSION

This case study presents the successful use of E-MVD in a centenarian patient suffering from TN, highlighting its potential as a viable treatment option even in this advanced age group. Further studies are needed to confirm these findings and explore the generalizability of this approach.

摘要

背景

内镜下微血管减压术(E-MVD)是治疗三叉神经痛(TN)的一种成熟有效的治疗方法。然而,其在超高龄患者,尤其是百岁老人中的应用从未有过记录。

病例描述

一名患有三叉神经痛五年的百岁老人于2020年1月到我院就诊。在过去三个月里,她的症状逐渐加重。尽管年事已高,但基于全面的体格检查和实验室检查,她的器官功能仍相对保留。实施了内镜下微血管减压术,患者疼痛立即缓解,且无任何神经功能障碍。在五年的随访中,症状未复发;该患者在105岁时仍无症状。

结论

本病例研究展示了内镜下微血管减压术在一名患有三叉神经痛的百岁老人中的成功应用,突出了其即使在这个高龄组中作为一种可行治疗选择的潜力。需要进一步研究来证实这些发现并探索这种方法的普遍性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6057/12375612/a9222424810d/fsurg-12-1537318-g001.jpg

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