Republic of Turkey Ministry of Health Ankara City Hospital, Obstetrics and Gynecology Department, Ankara, Turkey.
Malatya Training and Research Hospital, Department of Obstetrics and Gynecology, Perinatology Clinic, Malatya, Turkey.
J Obstet Gynaecol Res. 2022 Oct;48(10):2514-2521. doi: 10.1111/jog.15361. Epub 2022 Jul 11.
We aimed to show the predictive value of fetal adrenal gland volume (FAGV) measurement in the success of labor induction with oxytocin.
This is a prospective cohort study that included a total of 103 term nulliparous. Immediately after deciding to induce labor with oxytocin, the fetal right and left adrenal gland measurements were obtained.
Induction success was achieved in 89 of 103 (86.4%) pregnant women. In comparison of the FAGV values of failed induction labor group, the total volumes of right and left fetal adrenal glands and the fetal zone volumes (FZV) were found to be statistically significantly higher in the successful labor induction group (p < 0.001). In predicting induction success, the cut-off value of fetal adrenal gland volume (cFAGV) was set as >230.2 mm /kg and area under curve (AUC) value of 0.872 (95% confidence interval [CI], 0.736-1.000) for right total adrenal gland (p < 0.001). The cut-off value of cFAGV was set as >236.7 mm /kg and AUC value of 0.891(95%CI, 0.768-1.000) (p < 0.001) for left total adrenal gland. The cut-off value of cFAGV was set as >12.6 mm /kg and AUC value of 0.952 (95%CI, 0.905-0.999) for right FZV(p < 0.001). The cut-off value of cFAGV was set as >7.8 mm /kg and AUC value of 0.884 (95%CI, 0.752-1.000) for left FZV (p < 0.001).
Two-dimension ultrasonographic measurement is an easy-to-access and noninvasive method that can be integrated into the algorithms to predict the success of induction based on FAGV measurement.
旨在展示胎儿肾上腺体积（FAGV）测量在催产素引产成功率中的预测价值。
这是一项前瞻性队列研究，共纳入 103 例足月初产妇。在决定使用催产素引产后，立即测量胎儿右、左肾上腺的大小。
103 例孕妇中，89 例（86.4%）引产成功。与引产失败组相比，引产成功组的胎儿右、左肾上腺总容积和胎儿区容积（FZV）的 FAGV 值明显更高（p<0.001）。预测引产成功率时，将胎儿肾上腺体积的截断值（cFAGV）设定为>230.2mm/kg，右肾上腺总容积的曲线下面积（AUC）值为 0.872（95%置信区间[CI]：0.736-1.000）（p<0.001）。将左肾上腺总容积的 cFAGV 截断值设定为>236.7mm/kg，AUC 值为 0.891（95%CI：0.768-1.000）（p<0.001）。将右 FZV 的 cFAGV 截断值设定为>12.6mm/kg，AUC 值为 0.952（95%CI：0.905-0.999）（p<0.001）。将左 FZV 的 cFAGV 截断值设定为>7.8mm/kg，AUC 值为 0.884（95%CI：0.752-1.000）（p<0.001）。
二维超声测量是一种易于获得且无创的方法，可以整合到基于 FAGV 测量的预测引产成功率的算法中。
