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伊朗儿童和青少年头痛障碍的患病率:一项基于学校的研究。

The prevalence of headache disorders in children and adolescents in Iran: a schools-based study.

机构信息

Headache Department, Iranian Center of Neurological Research, Institute of Neuroscience, Tehran University of Medical Sciences, Tehran, Iran.

Cardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

出版信息

Cephalalgia. 2022 Oct;42(11-12):1246-1254. doi: 10.1177/03331024221103814. Epub 2022 Jul 11.

Abstract

BACKGROUND

While the Global Burden of Disease study reports headache disorders as the third-highest cause of disability worldwide, the headache data in this study largely come from adults. This national study in Iran, the first of its type in the Eastern Mediterranean Region, was part of a global schools-based programme within the Global Campaign against Headache contributing data from children (6-11 years) and adolescents (12-17 years).

METHODS

We followed the generic protocol for the global study. In a cross-sectional survey, self-completed structured questionnaires were administered to pupils within their classes in 121 schools selected from across the country to be representative of its diversities. Headache diagnostic questions were based on ICHD-3 criteria but for the inclusion of undifferentiated headache.

RESULTS

Of 3,357 potential participants, 3,244 (children 1,308 [40.3%], adolescents 1,936 [59.7%]; males 1,531 [47.2%], females 1,713 [52.8%]) satisfactorily completed the questionnaire. Children and males were therefore somewhat under-represented, with a participating proportion of 96.6%. Gender- and age-adjusted 1-year prevalence of any headache was 65.4%, of migraine 25.2%, of tension-type headache 12.7%, of undifferentiated headache 22.1%, of all headache on ≥15 days/month 4.1%, and of probable medication-overuse headache 1.1%. All headache types except undifferentiated headache were more prevalent among adolescents than children; probable medication-overuse headache increased five-fold between childhood and adolescence.

CONCLUSIONS

Headache disorders are common in children and adolescents in Iran, with undifferentiated headache accounting for over one third of cases. The increasing prevalence of probable medication-overuse headache with age is concerning. These findings are of importance to health and educational policies in Iran.

摘要

背景

虽然全球疾病负担研究报告称头痛障碍是全球第三大致残原因,但该研究中的头痛数据主要来自成年人。这项在伊朗进行的全国性研究是东地中海区域此类研究中的首例,它是全球学校头痛防治计划的一部分,该计划从儿童(6-11 岁)和青少年(12-17 岁)中收集数据。

方法

我们遵循全球研究的通用方案。在一项横断面调查中,在全国范围内选择的 121 所学校的班级内,向学生发放了自我填写的结构化问卷,这些学校具有代表性,可反映伊朗的多样性。头痛诊断问题基于 ICHD-3 标准,但纳入了未分化性头痛。

结果

在 3357 名潜在参与者中,有 3244 名(儿童 1308 名[40.3%],青少年 1936 名[59.7%];男性 1531 名[47.2%],女性 1713 名[52.8%])满意地完成了问卷。因此,儿童和男性的代表性略有不足,参与率为 96.6%。性别和年龄调整后的 1 年任何头痛的患病率为 65.4%,偏头痛为 25.2%,紧张型头痛为 12.7%,未分化性头痛为 22.1%,每月头痛≥15 天的比例为 4.1%,可能因药物滥用引起的头痛为 1.1%。除未分化性头痛外,所有头痛类型在青少年中的患病率均高于儿童;可能因药物滥用引起的头痛在儿童期到青春期之间增加了五倍。

结论

头痛障碍在伊朗儿童和青少年中很常见,未分化性头痛占病例的三分之一以上。随着年龄的增长,可能因药物滥用引起的头痛的患病率不断增加,这令人担忧。这些发现对伊朗的卫生和教育政策具有重要意义。

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