Babić U, Pejcić P, Djuricić Z, Grujicić S, Janković S, Vucinić M
Cor Vasa. 1987;29(1):1-8.
Using a mobile X-ray unit in the coronary care unit (CCU), intracoronary streptokinase (IC STK) administration was performed in 20 patients with acute myocardial infarction who arrived 2 to 5 hours after onset of symptoms. IC STK was infused at a rate of 4000 U/min. Of 20 patients, 17 had complete and 3 subtotal occlusion of the infarct-related artery. The IC STK infusion resulted within 15 to 80 min in reperfusion in 12 of 17 patients with occluded artery (70%). One patient died, 4 patients underwent early bypass grafting, in one PTCA was attempted and in one a femoral A-V fistula caused by the procedure required surgical revision. IC STK infusion is much more economical if performed in the CCU and the 24-hour coverage can be provided by an experienced invasive cardiologist on call service.
在冠心病监护病房（CCU）使用移动X线设备，对20例症状发作后2至5小时就诊的急性心肌梗死患者进行了冠状动脉内链激酶（IC STK）给药。IC STK以4000 U/分钟的速率输注。20例患者中，17例梗死相关动脉完全闭塞，3例次全闭塞。IC STK输注在15至80分钟内使17例闭塞动脉患者中的12例（70%）实现再灌注。1例患者死亡，4例患者接受了早期搭桥手术，1例尝试了经皮冠状动脉腔内血管成形术（PTCA），1例因该操作导致股动静脉瘘需要手术修复。如果在CCU进行IC STK输注则更为经济，并且可以由经验丰富的介入心脏病专家随时待命提供24小时服务。
