Castro Daniela V, Malhotra Jasnoor, Meza Luis, Govindarajan Ameish, Philip Errol J, Pal Sumanta K
City of Hope Comprehensive Cancer Center, Duarte, California, USA.
University of California-San Francisco, San Francisco, California, USA.
JACC CardioOncol. 2022 Jun 21;4(2):271-275. doi: 10.1016/j.jaccao.2022.04.004. eCollection 2022 Jun.
• With several newly approved regimens for RCC, cardiovascular risks must be considered during treatment selection. • Although uncommon, toxicities associated with these systemic therapies can have shortterm and long-term implications. • Although some toxicities may be lethal, others can be managed with early intervention. • As further agents are developed, multidisciplinary expertise is needed to manage associated cardiovascular toxicities.
• 对于几种新批准的肾癌治疗方案,在选择治疗方法时必须考虑心血管风险。
• 虽然不常见,但与这些全身治疗相关的毒性可能会产生短期和长期影响。
• 虽然有些毒性可能是致命的,但其他毒性可以通过早期干预来控制。
• 随着更多药物的研发,需要多学科专业知识来管理相关的心血管毒性。