Medical Scientist Training Program, Vanderbilt University School of Medicine, Nashville, TN, USA.
Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, 1215 21st Avenue South, Medical Center East, South Tower, Room 8310, Nashville, TN, 37232, USA.
J Autism Dev Disord. 2023 Mar;53(3):947-962. doi: 10.1007/s10803-022-05656-2. Epub 2022 Jul 11.
Interoception, the body's perception of its own internal states, is thought to be altered in autism, though results of empirical studies have been inconsistent. The current study systematically reviewed and meta-analyzed the extant literature comparing interoceptive outcomes between autistic (AUT) and neurotypical (NT) individuals, determining which domains of interoception demonstrate robust between-group differences. A three-level Bayesian meta-analysis compared heartbeat counting performance, heartbeat discrimination performance, heartbeat counting confidence ratings, and self-reported interoceptive attention between AUT and NT groups (15 studies; n = 467, n = 478). Autistic participants showed significantly reduced heartbeat counting performance [g = - 0.333, CrI (- 0.535, - 0.138)] and higher confidence in their heartbeat counting abilities [g = 0.430, CrI (0.123, 0.750)], but groups were equivalent on other meta-analyzed outcomes. Implications for future interoception research in autism are discussed.
内感受，即身体对自身内部状态的感知，被认为在自闭症中发生改变，尽管实证研究的结果并不一致。本研究系统地回顾和荟萃分析了现有的文献，比较了自闭症（AUT）和神经典型（NT）个体的内感受结果，确定了哪些内感受领域存在明显的组间差异。一项三级贝叶斯荟萃分析比较了 AUT 和 NT 组在心跳计数表现、心跳辨别表现、心跳计数置信度评分和自我报告的内感受注意方面的差异（15 项研究；n=467，n=478）。自闭症参与者的心跳计数表现明显下降[g=-0.333，CrI（-0.535，-0.138）]，对自己的心跳计数能力的信心更高[g=0.430，CrI（0.123，0.750）]，但在其他荟萃分析的结果上两组没有差异。讨论了自闭症内感受研究的未来意义。
