Geller Joseph S, Allegra Paul R, Seldon Crystal S, Spieler Benjamin O, Cohen Lara L, Barnhill Spencer W, Huntley Samuel R, Samuels Stuart, Wang Lora, Isrow Derek, Zerda Alberto De La, Wolfson Aaron H, Hernandez Giselle, Vilella Fernando E, Yechieli Raphael L
University of Miami Miller School of Medicine.
University of Miami Miller School of Medicine-Department of Orthopedic Surgery.
J Surg Orthop Adv. 2022 Summer;31(2):113-118.
Prophylactic radiotherapy (XRT) is a commonly used treatment to decrease heterotopic ossification (HO) in patients with traumatic hip injuries. We conducted a retrospective review of patients at risk for HO who underwent XRT. Of the patients reviewed, 27.3% developed radiographic HO, 11.2% developed symptoms, and 2.0% required resection surgery. Patients were divided into primary (n = 71) and secondary prophylaxis (n = 27) cohorts. In the primary group, 25.0% developed radiographic HO, 5.6% developed symptoms, and 0 required surgery. In the secondary cohort, 33.3% of patients developed new radiographic HO, and 25.9% were symptomatic: four had a Brooker score of 3, and three had a score of 4 (p = 0.03), and 7.4% required surgical resection. (Journal of Surgical Orthopaedic Advances 31(2):113-118, 2022).
预防性放射治疗（XRT）是一种常用的治疗方法，用于降低创伤性髋部损伤患者发生异位骨化（HO）的风险。我们对接受XRT治疗的有HO风险的患者进行了回顾性研究。在纳入研究的患者中，27.3%出现了影像学HO，11.2%出现了症状，2.0%需要进行切除手术。患者被分为初级预防组（n = 71）和二级预防组（n = 27）。在初级预防组中，25.0%出现了影像学HO，5.6%出现了症状，无人需要手术。在二级预防组中，33.3%的患者出现了新的影像学HO，25.9%出现了症状：4例布鲁克分级为3级，3例为4级（p = 0.03），7.4%需要手术切除。（《外科骨科进展杂志》31(2):113 - 118, 2022）
