Department of Gastroenterology and Hepatology, Hakodate Goryoukaku Hospital, Hakodate, Hokkaido, Japan.
Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
BMJ Case Rep. 2022 Jul 12;15(7):e249614. doi: 10.1136/bcr-2022-249614.
A man in his 80s who had a history of diabetes mellitus and aortic valve replacement was referred to our hospital for treatment of early gastric cancer and underwent endoscopic submucosal dissection (ESD). Three days after ESD, the patient presented with low back pain and fever (38.7°). We initially considered adverse events associated with gastric ESD such as delayed perforation. Moreover, thromboembolism and infectious endocarditis were suspected because of his medical history. However, there were no remarkable findings suggestive of these diseases. Finally, based on the results of blood cultures and MRI, the diagnosis of pyogenic spondylitis (PS) was made. We administered antibiotics for 12 weeks, and the patient improved without neurological impairments. This case indicates that bacteraemia and subsequent PS can occur following gastric ESD. Physicians should not overlook the patient's physical signs related to various adverse events after ESD.
一位 80 多岁的男性,有糖尿病和主动脉瓣置换术病史,因早期胃癌被转诊到我院接受内镜黏膜下剥离术(ESD)治疗。ESD 后 3 天,患者出现腰痛和发热(38.7℃)。我们最初考虑与胃 ESD 相关的不良事件,如延迟穿孔。此外,鉴于他的病史,还怀疑有血栓栓塞和感染性心内膜炎。然而,没有发现提示这些疾病的显著发现。最后,根据血培养和 MRI 的结果,诊断为化脓性脊柱炎(PS)。我们给予抗生素治疗 12 周,患者病情改善,无神经功能障碍。该病例表明,胃 ESD 后可发生菌血症和随后的 PS。医生不应忽视 ESD 后与各种不良事件相关的患者体征。