Huttelmaier Moritz Till, Herting Jonas, Fischer Thomas Horst
Department of Internal Medicine I, University of Wuerzburg, University Clinic, Oberdürrbacherstraße 6, D-97080 Wuerzburg, Germany.
Eur Heart J Case Rep. 2022 Jun 28;6(7):ytac250. doi: 10.1093/ehjcr/ytac250. eCollection 2022 Jul.
Implantable cardioverter defibrillators (ICDs) are most effective in treating sudden cardiac death. However, accurate diagnostic workup of broad complex tachycardia is crucial to ensure correct indication for ICD treatment and to avoid unnecessary invasive treatment and device-associated morbidity.
We present a case of atypical atrial flutter with 2:1 atrioventricular (AV) conduction via a left-posterior accessory pathway (AP), leading to the diagnosis of Wolff-Parkinson-White (WPW) syndrome. Upon admission, the 72-year-old patient showed a regular broad complex tachycardia with superior axis and positive concordance in precordial leads, suggestive of either ventricular tachycardia (VT), antidromic AV re-entrant tachycardia (AVRT), or supraventricular tachycardia with antegrade conduction via a left-posterior AP. Interrogation of the two-chamber ICD, which was very likely implanted unjustified in a peripheral clinic before, revealed atrial flutter with 2:1 AV conduction. Remarkably, after the restoration of sinus rhythm, no classic echocardiogram (ECG) criteria for preexcitation syndrome were detected. An invasive electrophysiological study proved the diagnosis of a bidirectionally conducting, left-posterior AP, which was successfully ablated.
Differential diagnosis of broad complex tachycardia with superior axis and positive concordance of chest leads consists of i) VT with a left ventricular exit at the posterior mitral annulus, ii) antidromic AVRT involving a left-posterior AP, and iii) supraventricular tachycardia predominantly conducted via a left-posterior AP. The absence of classic ECG criteria for preexcitation syndrome does not rule out AP sufficiently, highlighting the importance of minimal surface-ECG preexcitation criteria. In the case of detection of minimal surface-ECG preexcitation criteria, administration of adenosine rules out or proves the existence of an AP noninvasively and cost-effectively.
植入式心脏复律除颤器(ICD)在治疗心源性猝死方面最为有效。然而,对宽QRS波心动过速进行准确的诊断检查对于确保ICD治疗的正确适应症以及避免不必要的侵入性治疗和与设备相关的发病率至关重要。
我们报告一例非典型心房扑动,通过左后旁路(AP)呈2:1房室(AV)传导,导致诊断为预激综合征(WPW)。入院时,这位72岁的患者表现为规则的宽QRS波心动过速,电轴上偏,胸前导联呈正向同向性,提示室性心动过速(VT)、逆向型房室折返性心动过速(AVRT)或通过左后AP前传的室上性心动过速。对双腔ICD进行询问,该ICD之前很可能在外围诊所植入不当,结果显示为2:1房室传导的心房扑动。值得注意的是,恢复窦性心律后,未检测到预激综合征的经典心电图(ECG)标准。有创电生理研究证实诊断为双向传导的左后AP,并成功进行了消融。
电轴上偏且胸前导联正向同向性的宽QRS波心动过速的鉴别诊断包括:i)二尖瓣后环处左心室出口的VT,ii)涉及左后AP的逆向型AVRT,以及iii)主要通过左后AP传导的室上性心动过速。预激综合征经典ECG标准的缺失并不能充分排除AP的存在,这突出了最小体表ECG预激标准的重要性。在检测到最小体表ECG预激标准的情况下,使用腺苷可无创且经济高效地排除或证实AP的存在。