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儿童房间隔缺损的经导管封堵术:单中心经验及中期随访结果

Transcatheter Closure of Atrial Septal Defect in Children: Single-Center Experience, Mid-Term Follow-up Results.

作者信息

Özbay Yeşfa Şebnem, Eker Rukiye, Dindar Aygün, Aydoğan Ümrah, Nişli Kemal

机构信息

Department of Pediatrics, Agrı Training and Research Hospital, Ağrı, Turkey; Department of Pediatric Cardiology, İstanbul University, Faculty of Medicine, İstanbul, Turkey.

Department of Pediatric Cardiology, İstanbul University, Faculty of Medicine, İstanbul, Turkey.

出版信息

Turk Arch Pediatr. 2022 Jul;57(4):406-412. doi: 10.5152/TurkArchPediatr.2022.21307.

Abstract

OBJECTIVE

Atrial septal defect is a congenital heart disease usually diagnosed in childhood. This study aimed to evaluate the mid-term follow-up results of patients who underwent trans- catheter closure of atrial septal defect by comparing the devices and methods used in the procedure and investigating the complications of this procedure in children.

MATERIALS AND METHODS

This study evaluated 232 patient files retrospectively. Of the 232 patients, 24 were excluded from the study due to missing files or data. Also, patients with multi-fenestrated atrial septal defect and aneurismatic septal tissue were excluded from the study. The following data were evaluated: follow-up time, patient complaints, symptoms, trans- thoracic echocardiography, and transesophageal echocardiography findings (if performed), the size of the defect as measured by balloon-sizing, the size of the device used in the proce- dure, and major and minor complications.

RESULTS

The study included 208 children who were diagnosed with atrial septal defect. The mean age of the patients was 88.0 ± 56.5 months. Of the patients, 170 (81.7%) had no com- plaints. The success rate of the procedure was found to be 95.7%. While device embolization was the most common major complication, arrhythmia was the most common minor complica- tion. The complication rate was statistically different according to the device type used in the procedure.

CONCLUSION

Transcatheter closure of atrial septal defect is a safe method for atrial septal defect closure in pediatric patients. The study found that defect diameters measured by differ- ent methods were not correlated with each other. The procedure complication rates differed according to device type.

摘要

目的

房间隔缺损是一种通常在儿童期被诊断出的先天性心脏病。本研究旨在通过比较经导管封堵房间隔缺损所使用的器械和方法,并调查该手术在儿童中的并发症,来评估接受该手术患者的中期随访结果。

材料与方法

本研究对232份患者档案进行回顾性评估。在这232例患者中,24例因档案或数据缺失而被排除在研究之外。此外,多筛孔型房间隔缺损和动脉瘤样间隔组织的患者也被排除在研究之外。评估了以下数据:随访时间、患者主诉、症状、经胸超声心动图和经食管超声心动图检查结果(如进行了该项检查)、通过球囊测量的缺损大小、手术中使用的器械大小以及主要和次要并发症。

结果

该研究纳入了208例被诊断为房间隔缺损的儿童。患者的平均年龄为88.0±56.5个月。其中170例(81.7%)患者无主诉。该手术的成功率为95.7%。器械栓塞是最常见的主要并发症,而心律失常是最常见的次要并发症。根据手术中使用的器械类型,并发症发生率在统计学上存在差异。

结论

经导管封堵房间隔缺损是小儿患者房间隔缺损封堵的一种安全方法。该研究发现,通过不同方法测量的缺损直径彼此不相关。手术并发症发生率因器械类型而异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d52e/9319267/bb67d67d28dc/tap-57-4-406_f002.jpg

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