Siddiqui Waleed T, Usman Tariq, Atiq Mehnaz, Amanullah Muhammad Muneer
Dow University of Health Sciences, Karachi, Pakistan.
Department of Cardiothoracic Surgery, The Aga Khan University Hospital (AKUH), Karachi, Pakistan.
J Cardiovasc Thorac Res. 2014;6(4):205-10. doi: 10.15171/jcvtr.2014.013. Epub 2014 Dec 30.
This study compares the effectiveness and cost of trans-catheter verses surgical closure of secundum atrial septum defect (ASD). ASD accounts for 10% of congenital cardiac defects. Trans-catheter closure of secundum ASD is increasingly used as the primary intervention. Surgical repair is advised in a proportion of secundum type defects which are unsuitable for device closure.
We reviewed the clinical course of 176 patients who underwent closure of isolated secundum ASD. The patients were assigned to either the device or surgical group depending upon the treatment they received. Successful closure was assessed immediately after the procedure. The following outcomes were studied: mortality, morbidity, hospital stay, and costs.
Ninety five patients were in the surgical group and 81 patients were in the group undergoing device closure. The median age was 14.0 years (range 1.1-61.0) for surgical group and 24.0 years (range 0.5-68.0) for the device group. The mortality in both groups was 0. The procedure success rate was 100% for the surgical group and 96.3% for the device group. The complication rate was 13.7% for surgical group and 7.4% for the device group. The mean length of hospital stay was 5.0 ± 2.7 days for surgical group and 3.0 ± 0.4 days for device group. The procedure cost for surgery was found to be 12.3% lower than that of trans-catheter closure.
Successful closure is achieved by both methods. Trans-catheter closure results in lower rate of complication and hospital stay but the cost of the procedure tends to be higher than surgery.
本研究比较了经导管封堵与手术闭合继发孔型房间隔缺损(ASD)的有效性和成本。ASD占先天性心脏缺陷的10%。经导管闭合继发孔型ASD越来越多地被用作主要干预措施。对于一部分不适合器械封堵的继发孔型缺损,建议进行手术修复。
我们回顾了176例接受孤立性继发孔型ASD闭合术患者的临床病程。根据患者接受的治疗,将其分为器械组或手术组。术后立即评估封堵是否成功。研究了以下结果:死亡率、发病率、住院时间和成本。
手术组95例患者,器械封堵组81例患者。手术组的中位年龄为14.0岁(范围1.1 - 61.0岁),器械组为24.0岁(范围0.5 - 68.0岁)。两组的死亡率均为0。手术组的手术成功率为100%,器械组为96.3%。手术组的并发症发生率为13.7%,器械组为7.4%。手术组的平均住院时间为5.0±2.7天,器械组为3.0±0.4天。发现手术的费用比经导管封堵低12.3%。
两种方法均能成功闭合。经导管封堵导致较低的并发症发生率和住院时间,但手术费用往往高于手术。