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尼日利亚非洲人群癫痫的患病率:一项基于社区的研究。

Prevalence of the epilepsies in Nigerian Africans: a community-based study.

作者信息

Osuntokun B O, Adeuja A O, Nottidge V A, Bademosi O, Olumide A, Ige O, Yaria F, Bolis C L, Schoenberg B S

出版信息

Epilepsia. 1987 May-Jun;28(3):272-9. doi: 10.1111/j.1528-1157.1987.tb04218.x.

Abstract

A door-to-door survey to detect commonly occurring neurologic diseases was carried out in Igbo-Ora, a large Nigerian town with a population of approximately 20,000. Effective health care facilities have been operating in the community since 1963. Primary health care workers and nondoctor personnel administered a complete census, a screening questionnaire, and a simple screening neurologic examination. The pretested screening questionnaire had been shown in a pilot study to have a sensitivity of 95% for identifying those with epilepsy. Individuals positive on the screening phase of the survey were evaluated by neurologists and neurosurgeons, who used well-defined criteria to make the diagnosis. There were 101 (48 males and 53 females) who suffered from active epilepsy (5.3 cases/1,000) on prevalence day. The highest age-specific prevalence ratios occurred in those below age 20. The most common of the identifiable seizure types was complex partial seizures (52 cases). The prevalence ratio of epilepsy in this Nigerian town (with an effective health care system) is similar to that reported in some developed countries and several times lower than figures derived from studies in developing countries. These data suggest that an improved health care system would probably reduce the prevalence and burden of epilepsy in developing countries.

摘要

在伊博奥勒开展了一项挨家挨户的调查,以检测常见的神经系统疾病。伊博奥勒是尼日利亚的一个大城镇,人口约2万。自1963年以来,社区内一直设有有效的医疗保健设施。初级卫生保健工作者和非医生人员进行了全面普查、筛查问卷和简单的神经系统筛查检查。在一项试点研究中,经过预测试的筛查问卷对识别癫痫患者的敏感性为95%。调查筛查阶段呈阳性的个体由神经科医生和神经外科医生进行评估,他们使用明确的标准进行诊断。在患病率调查日,有101人(48名男性和53名女性)患有活动性癫痫(5.3例/1000人)。特定年龄患病率最高的是20岁以下人群。可识别的癫痫发作类型中最常见的是复杂部分性发作(52例)。这个拥有有效医疗保健系统的尼日利亚城镇的癫痫患病率与一些发达国家报告的患病率相似,比发展中国家研究得出的数据低几倍。这些数据表明,改善医疗保健系统可能会降低发展中国家癫痫的患病率和负担。

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