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一种使用外周静脉注入氙127对右心室进行成像的新方法。

A new method of imaging the right ventricle using peripheral vein infusion of xenon 127.

作者信息

Rodrigues E A, Lahiri A, Hinge D A, Smith T, Crawley J C, Raftery E B

出版信息

Eur J Nucl Med. 1987;12(12):617-9. doi: 10.1007/BF00284538.

DOI:10.1007/BF00284538
PMID:3582398
Abstract

We report the development of a new method for obtaining right ventriculograms using the peripheral intravenous infusion of a new tracer, 127Xe dissolved in saline. This tracer has a half life of 36 days, emits 172 keV and 203 keV photons, and is completely cleared by the lungs during pulmonary transit. The right ventricle can therefore be imaged free from interfering activity in the systemic circulation. The technique was used in 11 normal subjects and the results compared with those obtained using first pass and gated equilibrium blood pool angiography with 99mTc. Excellent images of the right ventricle were obtained and the tricuspid and pulmonary valve planes could be easily identified. This imaging technique has significant advantages over existing methods for the noninvasive assessment of right ventricular function.

摘要

我们报告了一种新方法的开发,该方法通过外周静脉输注一种新的示踪剂——溶解于盐水中的127Xe来获取右心室造影。这种示踪剂的半衰期为36天,发射172keV和203keV光子,在肺循环过程中完全被肺部清除。因此,右心室可以在不受体循环干扰活动的情况下成像。该技术应用于11名正常受试者,并将结果与使用99mTc进行首次通过和门控平衡血池血管造影所获得的结果进行比较。获得了右心室的优质图像,并且可以轻松识别三尖瓣和肺动脉瓣平面。这种成像技术在无创评估右心室功能方面比现有方法具有显著优势。

相似文献

1
A new method of imaging the right ventricle using peripheral vein infusion of xenon 127.一种使用外周静脉注入氙127对右心室进行成像的新方法。
Eur J Nucl Med. 1987;12(12):617-9. doi: 10.1007/BF00284538.
2
Krypton-81m imaging of the right ventricle.氪-81m对右心室的成像。
J Nucl Med. 1985 Jan;26(1):33-6.
3
Gated xenon scans for right ventricular function.用于评估右心室功能的门控氙扫描。
J Nucl Med. 1986 May;27(5):609-15.
4
[Right ventricular function assessed by scintigraphy using continuous infusion of krypton-81 m].
J Cardiogr Suppl. 1986(8):53-62.
5
Intravenous xenon- 133 for the determination of radionuclide first pass right ventricular ejection fraction.静脉注射氙-133用于测定放射性核素首次通过时的右心室射血分数。
Am J Cardiol. 1981 Mar;47(3):626-30. doi: 10.1016/0002-9149(81)90547-6.
6
Right ventricular ejection fraction measured by first-pass intravenous krypton-81m: reproducibility and comparison with technetium-99m.通过首次通过静脉注射氪-81m测量右心室射血分数:可重复性及与锝-99m的比较
Am J Cardiol. 1985 Nov 1;56(12):776-80. doi: 10.1016/0002-9149(85)91135-x.
7
Equilibrium radionuclide gated angiography in patients with tricuspid regurgitation.
Am J Cardiol. 1983 Jan 15;51(2):305-10. doi: 10.1016/s0002-9149(83)80055-1.
8
An improved method of right ventricular gated equilibrium blood pool radionuclide ventriculography.
Chest. 1982 Nov;82(5):607-14. doi: 10.1378/chest.82.5.607.
9
Videodensitometric ejection fraction from intravenous digital subtraction right ventriculograms: correlation with first pass radionuclide ejection fraction.
J Am Coll Cardiol. 1985 Jun;5(6):1377-81. doi: 10.1016/s0735-1097(85)80351-x.
10
Xenon-127, a comparison with xenon-133 for ventilation studies.
J Nucl Med. 1977 Mar;18(3):221-5.

本文引用的文献

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冷加压刺激引起的左心室功能变化的时间演变。用放射性核素血管造影术和195m金进行评估。
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J Nucl Med. 1985 Jan;26(1):33-6.
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J Nucl Med. 1986 May;27(5):609-15.
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A new technique for assessing right ventricular ejection fraction using rapid multiple-gated equilibrium cardiac blood pool scintigraphy. Description, validation and findings in chronic coronary artery disease.
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