Silfverskiöld P, Rosén I, Risberg J
Eur Arch Psychiatry Neurol Sci. 1987;236(4):202-8. doi: 10.1007/BF00383849.
Changes in global EEG and global cerebral blood flow (CBF) and their relationship following electroconvulsive therapy (ECT) were studied in 21 depressed in-patients, examined before and after treatment during an ECT series and at follow-up. Two patterns of ECT action could be discerned: acute changes related to single ECT's. The effects on CBF were more marked at the beginning of the ECT series, while the EEG slowing became more pronounced towards the end; non-acute accumulating ECT effects which were insignificant for CBF, whereas the EEG slowing increased progressively during the ECT series. Thus acute and non-acute effects of ECT on EEG and CBF follow different patterns indicating independent seizure effects. They showed a different time course and few correlations were found, suggesting that CBF is more linked to cortical changes while EEG is probably more related to activity in deeper, subcortical structures.
对21名住院抑郁症患者在接受电休克治疗（ECT）系列前后及随访期间进行检查，研究了ECT治疗后全脑脑电图（EEG）和全脑脑血流量（CBF）的变化及其关系。可识别出两种ECT作用模式：与单次ECT相关的急性变化。在ECT系列开始时对CBF的影响更为明显，而脑电图减慢在接近结束时变得更加显著；非急性累积ECT效应，对CBF无显著影响，而脑电图减慢在ECT系列期间逐渐增加。因此，ECT对EEG和CBF的急性和非急性效应遵循不同模式，表明癫痫发作效应相互独立。它们显示出不同的时间进程，且相关性较少，这表明CBF与皮质变化的联系更为紧密，而EEG可能与更深层的皮质下结构活动更为相关。
