Rosén I, Silfverskiöld P
Eur Arch Psychiatry Neurol Sci. 1987;236(4):209-13. doi: 10.1007/BF00383850.
Frequency analysis of EEG was made during electroconvulsive therapy (ECT) in patients with depression. Acute effects were quantified by calculating differences of EEG power from before to after the induced seizure, and were found to correlate with the duration of the seizure but not with the time lapse following the seizure. Increases in delta power were much more pronounced at the end of the treatment series than at the beginning. Non-acute effects were quantified as the differences from before the first treatment to the pre-ECT EEG later in the series. Increases in delta power correlated with the accumulated seizure duration and positively with the time lapse from the previous seizure, suggesting that it takes considerable time for this effect to develop. The concept of two different sources of EEG slowing during the ECT series is supported by different correlations between acute and non-acute EEG slowing on the one hand and on the other symptoms of depression, anxiety, cognitive disturbances, and cerebral blood flow as presented elsewhere.
对抑郁症患者进行电休克治疗（ECT）期间，对脑电图（EEG）进行了频率分析。通过计算诱发癫痫发作前后EEG功率的差异来量化急性效应，发现其与癫痫发作的持续时间相关，但与癫痫发作后的时间间隔无关。与治疗系列开始时相比，δ波功率的增加在治疗系列结束时更为明显。非急性效应被量化为从第一次治疗前到系列后期ECT前EEG的差异。δ波功率的增加与累积癫痫发作持续时间相关，且与上一次癫痫发作后的时间间隔呈正相关，这表明这种效应的产生需要相当长的时间。ECT系列期间EEG减慢的两种不同来源的概念得到了支持，一方面是急性和非急性EEG减慢之间的不同相关性，另一方面是其他地方所呈现的抑郁、焦虑、认知障碍和脑血流量等症状之间的不同相关性。
