Lindell O
Eur Urol. 1987;13(1-2):17-21. doi: 10.1159/000472729.
Nineteen salvage cystectomies were performed during a period of 17 years, either on patients who failed definitive radiation therapy of bladder carcinoma or on those with massive bleeding or incapacitating irritative bladder symptoms after irradiation. In 16 cases a single-stage and in 3 a two-stage procedure was used. The postoperative hospital mortality rate was 11%. Early complications developed in 63%, late complications in 47% of the patients. The 5-year survival rate was 5%. In 11 cases, widespread transitional cell carcinoma was the cause of death. With more accurate preoperative tumor staging and subsequent patient selection, better results can be obtained by this procedure. A proposal for the treatment of patients with T3 bladder cancer is made.
在17年的时间里共进行了19例挽救性膀胱切除术，手术对象为膀胱癌根治性放疗失败的患者，或放疗后出现大出血或严重刺激性膀胱症状的患者。16例采用一期手术，3例采用二期手术。术后医院死亡率为11%。63%的患者出现早期并发症，47%的患者出现晚期并发症。5年生存率为5%。11例患者死于广泛的移行细胞癌。通过更准确的术前肿瘤分期和后续的患者选择，该手术可取得更好的效果。本文还提出了T3期膀胱癌患者的治疗建议。
