每日血浆置换过程中的血浆纤连蛋白水平。

Plasma fibronectin levels during daily plasmapheresis.

作者信息

Wahlin A, Holm J, Hansson M, Berghem L

出版信息

Eur J Haematol. 1987 Jan;38(1):39-42. doi: 10.1111/j.1600-0609.1987.tb01421.x.

DOI:10.1111/j.1600-0609.1987.tb01421.x

Abstract

Plasma fibronectin concentrations were studied in 10 patients with multiple myeloma. After plasma exchange for 3 d (2.5-3 l plasma daily) the plasma fibronectin decreased to about 50% of the initial level. Resynthesis of fibronectin seemed to increase during 3 d of plasmapheresis, and was sufficient to normalize plasma fibronectin concentration. The plasma fibronectin concentration reached the initial level within 2 d after interrupting plasmapheresis in spite of concurrent cytotoxic treatment. The patients studied showed no signs of infection.

摘要

对10例多发性骨髓瘤患者的血浆纤连蛋白浓度进行了研究。在进行3天的血浆置换（每天置换2.5 - 3升血浆）后，血浆纤连蛋白降至初始水平的约50%。在血浆置换的3天期间，纤连蛋白的再合成似乎增加，并且足以使血浆纤连蛋白浓度恢复正常。尽管同时进行了细胞毒性治疗，但在中断血浆置换后2天内，血浆纤连蛋白浓度达到了初始水平。所研究的患者未显示出感染迹象。