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[刺激边缘皮层和下丘脑不同结构时血管运动交感神经活动变化机制的比较研究]

[Comparative study of mechanisms of change in vasomotor sympathetic activity upon stimulation of different structures of the limbic cortex and hypothalamus].

作者信息

Baklavadzhian O G, Eganova V S, Kasparova S R, Skobelev V A, Khachatrian A V

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1987 Mar;73(3):373-83.

PMID:3582697
Abstract

Responses of arterial blood pressure to low- and high-frequency stimulation of different structures of the limbic cortex and hypothalamus were studied in anesthetized and immobilized cats. The low-frequency (5 Hz) stimulation induced depressor reactions, the high-frequency (100 Hz) one-pressor responses. Both kinds of stimulation in the dorsal level of area 25 and of area 23 of the limbic cortex and of the anterior hypothalamus induced similar depressor responses, whereas the hypothalamic structures in the posterolateral region induced only pressor responses. The role of poly-effectory, sympatho-inhibitory and sympatho-activating neurons responsible for the observed three patterns of the blood pressure changes in low- and high-frequency stimulation of limbic cortex and hypothalamus, is discussed.

摘要

在麻醉和固定的猫身上研究了动脉血压对边缘皮质和下丘脑不同结构的低频和高频刺激的反应。低频(5赫兹)刺激诱发降压反应,高频(100赫兹)刺激诱发升压反应。在边缘皮质25区和23区以及下丘脑前部的背侧水平进行的这两种刺激均诱发相似的降压反应,而后外侧区域的下丘脑结构仅诱发升压反应。文中讨论了多效应器、交感抑制和交感激活神经元在边缘皮质和下丘脑低频及高频刺激中所观察到的三种血压变化模式中的作用。

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