Fassl A, Muhr R, Pirker S, Nahler G
J Int Med Res. 1987 Mar-Apr;15(2):76-82. doi: 10.1177/030006058701500203.
Fifty patients with moderate or severe bronchitis were randomly allocated into groups receiving orally either 1000 mg amoxycillin twice daily or 750 mg three times daily. Overall cure rates (both 92%) and the incidence of side-effects (4% and 8%, respectively) were similar in both groups. A twice daily regimen, therefore, seems to be as effective as conventional treatment and has the advantage of being more convenient for the patient.
50例中度或重度支气管炎患者被随机分为两组,一组每天口服两次1000毫克阿莫西林,另一组每天口服三次750毫克阿莫西林。两组的总体治愈率(均为92%)和副作用发生率(分别为4%和8%)相似。因此,每日两次的治疗方案似乎与传统治疗同样有效,而且对患者来说更方便。