Duval-Beaupère G, Kaci M, Lougovoy J, Caponi M F, Touzeau C
Dev Med Child Neurol. 1987 Apr;29(2):225-31. doi: 10.1111/j.1469-8749.1987.tb02140.x.
Total body length and body segments (crown-rump length, sub-ischeal length) of 78 children with myelomeningocele were measured at regular intervals during growth for a mean duration of 4.4 years. These children were shown to have defective growth, with an increased upper segment/lower segment ratio. It was found that the higher the level of the meningocele the greater the growth defects. However, the relationship was statistically significant only for the first seven years of life. It is concluded that neurological damage was mainly responsible for defective growth during the first years of life, but that other factors independent of the level of the meningocele also come into play in later years.
在平均4.4年的生长期间,定期测量了78例脊髓脊膜膨出患儿的全身长度和身体节段(顶臀长度、坐骨下长度)。这些患儿表现出生长缺陷,上下段比例增加。结果发现,脑脊膜膨出的位置越高,生长缺陷越大。然而,这种关系仅在生命的前七年具有统计学意义。得出的结论是,神经损伤是生命最初几年生长缺陷的主要原因,但在随后几年中,与脑脊膜膨出位置无关的其他因素也发挥了作用。