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Short stature and the effect of human growth hormone: Guidelines for the care of people with spina bifida.身材矮小与人生长激素的作用：脊髓脊膜膨出患者护理指南。
J Pediatr Rehabil Med. 2020;13(4):549-555. doi: 10.3233/PRM-200710.
2
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3
Latex allergy guidelines for people with spina bifida.脊髓裂患者乳胶过敏指南。
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4
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J Pediatr Rehabil Med. 2020;13(4):621-627. doi: 10.3233/PRM-200744.
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Central precocious puberty in spina bifida children: Guidelines for the care of people with spina bifida.脊髓脊膜膨出患儿的中枢性性早熟：脊髓脊膜膨出人士照护指南。
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Nutrition, metabolic syndrome, and obesity: Guidelines for the care of people with spina bifida.营养、代谢综合征和肥胖：脊髓裂患者护理指南。
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Mental health guidelines for the care of people with spina bifida.脊髓裂患者护理的精神卫生指南。
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Family functioning guidelines for the care of people with spina bifida.脊髓裂患者护理的家庭功能指南。
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Quality of life: Guidelines for the care of people with spina bifida.生活质量：脊髓裂患者护理指南。
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Sexual health and education guidelines for the care of people with spina bifida.脊髓裂患者关怀的性健康和教育指南。
J Pediatr Rehabil Med. 2020;13(4):611-619. doi: 10.3233/PRM-200743.

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Evidence-based position paper of the UEMS PRM on the role of Physical and Rehabilitation Medicine (PRM) physician in the management of children and adults with spinal dysraphism.欧洲医学科学院物理医学与康复医学分会关于物理医学与康复医学医师在管理脊柱发育不良的儿童和成人中的作用的循证立场文件。
Eur J Phys Rehabil Med. 2022 Aug;58(4):511-519. doi: 10.23736/S1973-9087.22.07536-0. Epub 2022 May 16.

本文引用的文献

1
Scientific methodology of the development of the Guidelines for the Care of People with Spina Bifida: An initiative of the Spina Bifida Association.《脊髓脊膜膨出人士照护指南制定的科学方法学：脊髓脊膜膨出协会的一项倡议》。
Disabil Health J. 2020 Apr;13(2):100816. doi: 10.1016/j.dhjo.2019.06.005. Epub 2019 Jun 18.
2
Effect of recombinant human growth hormone therapy on blood lipid and carotid intima-media thickness in children with growth hormone deficiency.重组人生长激素治疗对生长激素缺乏症儿童血脂及颈动脉内膜中层厚度的影响。
Pediatr Res. 2018 May;83(5):954-960. doi: 10.1038/pr.2017.271. Epub 2018 Jan 17.
3
Muscle and skeletal health in children and adolescents with GH deficiency.生长激素缺乏症儿童和青少年的肌肉与骨骼健康
Best Pract Res Clin Endocrinol Metab. 2016 Dec;30(6):771-783. doi: 10.1016/j.beem.2016.11.012. Epub 2016 Nov 25.
4
Cut-off limits of the peak GH response to stimulation tests for the diagnosis of GH deficiency in children and adolescents: study in patients with organic GHD.儿童和青少年生长激素（GH）缺乏症诊断中刺激试验的GH峰值反应截断值：对器质性生长激素缺乏症患者的研究
Eur J Endocrinol. 2016 Jul;175(1):41-7. doi: 10.1530/EJE-16-0105. Epub 2016 May 4.
5
Fracture risk in adult patients treated with growth hormone replacement therapy for growth hormone deficiency: a prospective observational cohort study.生长激素缺乏症成年患者接受生长激素替代治疗后的骨折风险：一项前瞻性观察性队列研究。
Lancet Diabetes Endocrinol. 2015 May;3(5):331-8. doi: 10.1016/S2213-8587(15)00098-4. Epub 2015 Apr 12.
6
Advances in the care of children with spina bifida.脊柱裂患儿护理的进展。
Adv Pediatr. 2014 Aug;61(1):33-74. doi: 10.1016/j.yapd.2014.03.007.
7
Cluster of cardiometabolic risk factors in children with GH deficiency: a prospective, case-control study.生长激素缺乏症患儿的心血管代谢危险因素聚集：一项前瞻性病例对照研究。
Clin Endocrinol (Oxf). 2014 Jun;80(6):856-62. doi: 10.1111/cen.12393. Epub 2014 Jan 16.
8
Nominal group technique: an effective method for obtaining group consensus.名义群体技术：达成群体共识的有效方法。
Int J Nurs Pract. 2012 Apr;18(2):188-94. doi: 10.1111/j.1440-172X.2012.02017.x.
9
Methods of formal consensus in classification/diagnostic criteria and guideline development.分类/诊断标准和指南制定中的正式共识方法。
Semin Arthritis Rheum. 2011 Oct;41(2):95-105. doi: 10.1016/j.semarthrit.2010.12.001. Epub 2011 Mar 21.
10
Childhood growth hormone deficiency, bone density, structures and fractures: scrutinizing the evidence.儿童生长激素缺乏症、骨密度、结构和骨折：仔细审查证据。
Clin Endocrinol (Oxf). 2010 Mar;72(3):281-9. doi: 10.1111/j.1365-2265.2009.03686.x. Epub 2009 Aug 29.

身材矮小与人生长激素的作用：脊髓脊膜膨出患者护理指南。

Short stature and the effect of human growth hormone: Guidelines for the care of people with spina bifida.

机构信息

Riley Hospital for Children, Section of Developmental Pediatrics, Indianapolis, IN, USA.

Riley Hospital for Children, Section of Pediatric Endocrinology, Indianapolis, IN, USA.

出版信息

J Pediatr Rehabil Med. 2020;13(4):549-555. doi: 10.3233/PRM-200710.

DOI:10.3233/PRM-200710
PMID:32986629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7838964/
Abstract

It is estimated that a significant percentage of individuals with spina bifida (SB) are shorter than their age-matched typical peers. Parents of children with spina bifida may ask if human growth hormone is appropriate for their child. This article discusses short stature and the use of human growth hormone among children with SB. This guideline was developed for SB Healthcare Guidelines from the 2018 Spina Bifida Association's Fourth Edition of the Guidelines for the Care of People with Spina Bifida.

摘要

据估计，相当一部分脊柱裂（SB）患者的身高低于同龄典型同龄人。脊柱裂患儿的父母可能会询问是否适合其孩子使用人类生长激素。本文讨论了 SB 医疗保健指南中 SB 患儿的身材矮小和人类生长激素的使用问题。本指南是为 2018 年脊柱裂协会《脊柱裂患者护理指南》第四版制定的。