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[正常受试者和十二指肠溃疡患者胃蠕动的传播]

[Propagation of the gastric peristalsis in normal subjects and duodenal ulcer patients].

作者信息

Boiron M, Arhan P, Dorval E D, Rouleau P, Metman E H, Bertrand J, Thouvenot J

出版信息

Gastroenterol Clin Biol. 1987 Apr;11(4):312-8.

PMID:3582886
Abstract

The velocities of gastric peristaltic waves were measured on fluorographic series made in normal subjects and patients with duodenal ulcer. After an overnight fast, the subjects drank 250 ml of barium suspension. Sequential radiograms were taken every 2 s during 30 s after two pyloric ejections. Peristaltic waves were located and their displacements measured with an Apple Graphic Tablet. Wave progression diagrams and velocity histograms were drawn for each subject. The velocities were calculated every 2 s. A "spread index" Ip was determined for each subject, characterizing the irregularity of propagation. Mean frequency and mean velocity were greater in duodenal ulcer patients (3.6 c/min; 3.7 mm/s) than in normal subjects (2.9 c/min; 2.4 mm/s; p less than 0.001). Nevertheless, no significant difference was found between proximal or midcorpus and antral velocities, in ulcer patients as well as in normal subjects, contrarily to classical data. However, the velocities were not uniform along the stomach. The contractions spread unevenly and displayed transient slopes. The irregularities of propagation were more pronounced in normal subjects, ranging from 0 to 14 mm/s with 28 p. 100 of velocities less than 1 mm/s, then in ulcer patients (0 to 13 mm/s with 12 p. 100 of low velocities). The spread index Ip was greater in normal (ranged from 0.54 to 2.62) than in ulcer patients (ranged from 0.16 to 0.48; p less than 0.001). This study showed that the propagation velocity of the peristaltic waves and its regularity were different in normal subjects and in duodenal ulcer patients.

摘要

在正常受试者和十二指肠溃疡患者的荧光造影系列片上测量胃蠕动波的速度。经过一夜禁食后,受试者饮用250毫升钡剂混悬液。在两次幽门排空后的30秒内,每2秒拍摄一次连续的X光片。用苹果图形输入板确定蠕动波的位置并测量其位移。为每个受试者绘制波传播图和速度直方图。每2秒计算一次速度。为每个受试者确定一个“传播指数”Ip,以表征传播的不规则性。十二指肠溃疡患者的平均频率和平均速度(3.6次/分钟;3.7毫米/秒)高于正常受试者(2.9次/分钟;2.4毫米/秒;p<0.001)。然而,与经典数据相反,在溃疡患者和正常受试者中,近端或胃体中部与胃窦部的速度之间均未发现显著差异。但是,沿胃的速度并不均匀。收缩传播不均匀并显示出瞬时斜率。正常受试者中传播的不规则性更为明显,速度范围为0至14毫米/秒,其中28%的速度低于1毫米/秒,其次是溃疡患者(0至13毫米/秒,12%为低速)。正常受试者的传播指数Ip(范围为0.54至2.62)高于溃疡患者(范围为0.16至0.48;p<0.001)。这项研究表明,正常受试者和十二指肠溃疡患者的蠕动波传播速度及其规律性有所不同。

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