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美国兽医急救与危重病学学院院士在犬猫血管扩张性低血压治疗中使用血管加压药。

Use of vasopressors for treatment of vasodilatory hypotension in dogs and cats by Diplomates of the American College of Veterinary Emergency and Critical Care.

机构信息

Department of Clinical Studies and Advanced Medicine, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA.

Veterinary Information Network, Davis, California, USA.

出版信息

J Vet Emerg Crit Care (San Antonio). 2022 Nov;32(6):714-722. doi: 10.1111/vec.13230. Epub 2022 Jul 13.

Abstract

OBJECTIVE

To identify the most common practices of Diplomates of the American College of Veterinary Emergency and Critical Care (DACVECCs) as they relate to the recognition and treatment of hypotension in dogs and cats, particularly concerning the use of vasopressors in vasodilatory shock states.

DESIGN

A survey regarding vasopressor use was sent to all active DACVECCs using the Veterinary Information Network. Questions focused on respondent characteristics, method of recognition of hypotension, triggers for initiation of vasopressor therapy, first- and second-line vasopressor choice, and methods of determining response to therapy.

SUBJECTS

A total of 734 DACVECCs were invited to participate, and 203 Diplomates (27.7%) completed the survey.

RESULTS

For both dogs and cats, the most common first-line vasopressor was norepinephrine (87.9% in dogs and 83.1% in cats). The most common second-choice vasopressor was vasopressin (44.2% in dogs and 39.0% in cats). Cutoff values for initiating vasopressor therapy varied between species and modality used for blood pressure measurement. In general, most DACVECCs chose to initiate vasopressor therapy at a Doppler blood pressure <90 mm Hg or a mean arterial pressure of <60 or <65 mm Hg when using oscillometric or direct arterial blood pressure measurements in dogs and cats.

CONCLUSIONS

Most DACVECCs adhere to published human guidelines when choosing a first-line vasopressor. However, there is significant variability in blood pressure measurement technique, cutoffs for initiation of vasopressor use, and choice of second-line vasopressors.

摘要

目的

确定美国兽医急救与危重病学学院(DACVECC)院士在犬猫低血压的识别和治疗方面最常见的做法,特别是涉及血管加压剂在血管扩张性休克状态下的应用。

设计

使用兽医信息网络向所有现役 DACVECC 发送了一份关于血管加压剂使用的调查问卷。问题集中在受访者特征、低血压识别方法、启动血管加压剂治疗的触发因素、一线和二线血管加压剂选择以及确定治疗反应的方法。

对象

共有 734 名 DACVECC 受邀参与,其中 203 名(27.7%)完成了调查。

结果

对于犬和猫,最常用的一线血管加压剂是去甲肾上腺素(犬为 87.9%,猫为 83.1%)。最常用的二线血管加压剂是血管加压素(犬为 44.2%,猫为 39.0%)。启动血管加压剂治疗的截止值因物种和用于血压测量的方式而异。一般来说,大多数 DACVECC 选择在多普勒血压<90 mmHg 或平均动脉压<60 或<65 mmHg 时开始血管加压剂治疗,当使用振荡或直接动脉血压测量时,无论是犬还是猫。

结论

大多数 DACVECC 在选择一线血管加压剂时遵循已发表的人类指南。然而,血压测量技术、启动血管加压剂使用的截止值以及二线血管加压剂的选择存在显著差异。

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