Damiani Giovanni, Finelli Renata, Kridin Khalaf, Pacifico Alessia, Buja Alessandra, Bragazzi Nicola L, Malagoli Piergiorgio, Savoia Paola, Gironi Laura C, Grada Ayman, Conic Rosalynn R, Linder Dennis, Micali Giuseppe, Pigatto Paolo D
Clinical Dermatology, IRCCS Galeazzi Orthopedic Institute, Milan, Italy -
Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy -
Ital J Dermatol Venerol. 2022 Oct;157(5):419-423. doi: 10.23736/S2784-8671.22.07246-2. Epub 2022 Jul 13.
Wearing masks is an optimal preventive strategy during COVID-19 pandemic, but it may increase facial sebum production. However, few case reports have described seborrheic dermatitis (SeBD) and psoriasis (PsO) flares due to masks. Hence, we conducted a multicenter study to clarify the possibility of increased SeBD and PsO flares in association with mask wearing during the COVID-19 pandemic.
This multicenter study enrolled patients with a diagnosis of facial SeBD and PsO. All dermatological consultations were conducted in teledermatology at baseline (T0) and after 1 month (T1) Of >6 hours/day wearing mask. PsO patients were assessed using PsO Area and Severity Index (PASI) and self-administered PASI (SAPASI), whilst SeBD patients with symptom scale of seborrheic dermatitis' (SSSD) and seborrheic dermatitis area and severity index (SEDASI).
A total of 33 (20 males, 13 females, average age 43.61±9.86) patients with PsO and 33 (20 males, 13 females, average age 44.00±8.58) with SeBD were enrolled. After 1 month, PsO patients displayed higher values of both PASI and SAPASI (P<0.0001), while SeBD patients experienced a flare, as testified by the increment of both SSSD and SEDASI (P<0.0001). Mask type did not seem to influence the flare severity.
Masks remain an optimal preventive strategy during COVID-19 pandemic, but patients with PsO and SeBD may experience facial flares. Thus, therapeutic approach should be more aggressive in these groups of patients to counteract the triggering effect of masks.
在新冠疫情期间，佩戴口罩是一种最佳的预防策略，但这可能会增加面部皮脂分泌。然而，仅有少数病例报告描述了因佩戴口罩引发的脂溢性皮炎（SeBD）和银屑病（PsO）发作。因此，我们开展了一项多中心研究，以明确在新冠疫情期间，佩戴口罩与SeBD和PsO发作增加之间的关联。
这项多中心研究纳入了诊断为面部SeBD和PsO的患者。所有皮肤科会诊均通过远程皮肤病学在基线时（T0）以及每天佩戴口罩超过6小时1个月后（T1）进行。PsO患者使用银屑病面积和严重程度指数（PASI）以及自我管理的PASI（SAPASI）进行评估，而SeBD患者则使用脂溢性皮炎症状量表（SSSD）和脂溢性皮炎面积及严重程度指数（SEDASI）。
共纳入了33例（20例男性，13例女性，平均年龄43.61±9.86）PsO患者和33例（20例男性，13例女性，平均年龄44.00±8.58）SeBD患者。1个月后，PsO患者的PASI和SAPASI值均更高（P<0.0001），而SeBD患者出现了发作，这通过SSSD和SEDASI的增加得到证实（P<0.0001）。口罩类型似乎并未影响发作的严重程度。
在新冠疫情期间，口罩仍然是一种最佳的预防策略，但PsO和SeBD患者可能会出现面部发作。因此，对于这些患者群体，治疗方法应更积极，以抵消口罩的触发作用。
