Smith D A, Karmally W, Brown W V
Geriatrics. 1987 Jun;42(6):33-6, 39-42, 44.
There are elderly persons at increased risk of coronary heart disease due to elevated LDL cholesterol, lowered HDL cholesterol, or both. Risk difference data seem to indicate that the reduction in risk of coronary artery disease by lowering elevated cholesterol values is the same in the elderly as it is in younger persons. hence we recommend screening for total cholesterol in the elderly, followed by a fasting lipid profile in those with screening cholesterol values over 200 mg/dl (230 mg/dl by certain methods). Comparative LDL and HDL cholesterol values, as well as L/H ratios, are presented for assisting in assessment of results and for planning therapeutic strategy.
由于低密度脂蛋白胆固醇升高、高密度脂蛋白胆固醇降低或两者兼而有之,老年人患冠心病的风险增加。风险差异数据似乎表明,降低升高的胆固醇值对降低老年人冠状动脉疾病风险的作用与对年轻人的作用相同。因此,我们建议对老年人进行总胆固醇筛查,对于筛查胆固醇值超过200mg/dl(某些方法为230mg/dl)的人,随后进行空腹血脂检查。给出了低密度脂蛋白和高密度脂蛋白胆固醇的比较值以及L/H比值,以协助评估结果和制定治疗策略。