原发性肺淋巴上皮瘤样癌免疫治疗病例报告及文献复习。
Primary pulmonary lymphoepithelioma-like carcinoma treated with immunotherapy: A case report and literature review.
机构信息
Division of Medical Oncology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
出版信息
Thorac Cancer. 2022 Sep;13(17):2539-2541. doi: 10.1111/1759-7714.14580. Epub 2022 Jul 13.
Here, we report a case of metastatic Epstein-Barr virus (EBV)-related primary pulmonary lymphoepithelioma-like carcinoma (PPLELC) in a young, nonsmoking female who responded well to treatment with two types of immune checkpoint inhibitors (ICIs). This is the first case report of a favorable outcome to ICIs in the late-line treatment of advanced PPLELC patients with programmed cell death-ligand 1 (PD-L1) expression.
在这里，我们报告了一例转移性 Epstein-Barr 病毒（EBV）相关的原发性肺淋巴上皮瘤样癌（PPLELC）病例，该患者为年轻的非吸烟女性，对两种免疫检查点抑制剂（ICIs）的治疗反应良好。这是首例程序性细胞死亡配体 1（PD-L1）表达的晚期 PPLELC 患者接受 ICI 二线治疗后获得良好结局的病例报告。
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