Samuel Ankhita R, Fuhr Laura, DeGeorge Brent R, Black Jonathan, Campbell Christopher, Stranix John T
Department of Plastic Surgery, University of Virginia, Charlottesville, Virginia.
Arch Plast Surg. 2022 May 27;49(3):339-345. doi: 10.1055/s-0042-1744419. eCollection 2022 May.
Patients that undergo mastectomy for breast cancer with reconstruction may be prone to prolonged opioid use. As risk factors are not well-established, this article sought to better understand the risk factors that may be associated with this. Patients that underwent breast reconstruction between 2010 and 2018 were identified in PearlDiver, a national insurance claims database. Patient demographics and comorbidities were elucidated, and various complications were then identified. Descriptive statistics as well as a multivariate analysis was used to evaluate the association of risk factors and complications. Breast reconstruction patients of 24,765 were identified from this database. Obesity, tobacco use, benzodiazepine use, and anticonvulsant use were all associated with prolonged opioid prescriptions greater than 90 days after both alloplastic and autologous reconstruction. Prolonged opioid use continues to remain a topic of concern, and particularly in cancer patients that undergo breast reconstruction. Providers should be aware of potential risk factors for this to reduce this chance following breast reconstruction surgery.
接受乳腺癌乳房切除术后进行重建的患者可能容易长期使用阿片类药物。由于风险因素尚未完全明确，本文旨在更好地了解可能与此相关的风险因素。在全国保险理赔数据库PearlDiver中识别出2010年至2018年间接受乳房重建的患者。阐明了患者的人口统计学特征和合并症，然后识别出各种并发症。使用描述性统计以及多变量分析来评估风险因素与并发症之间的关联。从该数据库中识别出24765例乳房重建患者。肥胖、吸烟、使用苯二氮䓬类药物和抗惊厥药物均与接受人工材料乳房重建和自体乳房重建后超过90天的长期阿片类药物处方相关。长期使用阿片类药物仍然是一个令人担忧的问题，尤其是在接受乳房重建的癌症患者中。医疗服务提供者应意识到这一潜在风险因素，以减少乳房重建手术后出现这种情况的可能性。
