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迷走神经根入/出区微血管减压术对伴原发性高血压的面肌痉挛患者血压的影响:一项回顾性临床分析

Effect of Microvascular Decompression of the Vagus Root Entry/Exit Zone on Blood Pressure in Patients with Hemifacial Spasm Associated with Essential Hypertension: A Retrospective Clinical Analysis.

作者信息

Wei Xuefeng, Wang Jiao, Kong Xuerui, Gao Caibin, Wang Feng

机构信息

Department of Neurosurgery, Ningxia Medical University, Yinchuan, China.

Blood Purification Center, Wuxi No. 2 People's Hospital, Wuxi, China.

出版信息

J Neurol Surg B Skull Base. 2021 May 23;83(Suppl 2):e336-e342. doi: 10.1055/s-0041-1729178. eCollection 2022 Jun.

Abstract

This study aimed to evaluate blood pressure alterations after microvascular decompression (MVD) surgery in patients with hemifacial spasm (HFS) with coexisting hypertension (HTN).  A total of 56 patients with HFS with concurrent HTN who underwent MVD surgery in our center between 2015 and 2019 were retrospectively analyzed. Patients were divided into control and experimental groups: patients who received MVD treatment for only the facial nerve and those who received MVD for the affected facial nerve, ipsilateral vagus nerve, and adjacent ventrolateral medulla, respectively. Preoperative (3 days) and postoperative (7 days and 6 months) blood pressure measurements were analyzed.  No statistically significant differences were observed in gender, age, HFS course, HTN course, HTN grade, and preoperative blood pressure between the two groups. No significant difference was observed between pre- and postoperative blood pressure in the control group. In the experimental group, systolic blood pressure significantly differed between 3 preoperative days and 7 postoperative days (  < 0.05), as did diastolic blood pressure (  < 0.05). Measurement at 6 postoperative months also showed significant differences for both systolic blood pressure and diastolic blood pressure compared with that at 3 preoperative days (  < 0.05). HTN grade according to the World Health Organization classification criteria significantly differed between preoperative and postoperative measurements (  < 0.05).  Vascular decompression of the ipsilateral vagus nerve roots may improve blood pressure management in patients with HFS with coexisting HTN who undergo MVD. Laterality of involvement (left vs. right) did not significantly differ.

摘要

本研究旨在评估微血管减压术(MVD)治疗合并高血压(HTN)的面肌痉挛(HFS)患者术后的血压变化。 回顾性分析了2015年至2019年期间在本中心接受MVD手术的56例合并HTN的HFS患者。患者分为对照组和实验组:分别为仅接受面神经MVD治疗的患者以及接受患侧面神经、同侧迷走神经和邻近延髓腹外侧区MVD治疗的患者。分析术前(3天)和术后(7天和6个月)的血压测量值。 两组患者在性别、年龄、HFS病程、HTN病程、HTN分级和术前血压方面均未观察到统计学显著差异。对照组术前和术后血压无显著差异。在实验组中,术前3天和术后7天的收缩压有显著差异(<0.05),舒张压也有显著差异(<0.05)。术后6个月的测量结果显示,与术前3天相比,收缩压和舒张压均有显著差异(<0.05)。根据世界卫生组织分类标准,术前和术后测量的HTN分级有显著差异(<0.05)。 同侧迷走神经根的血管减压术可能改善接受MVD治疗的合并HTN的HFS患者的血压控制。受累侧别(左侧与右侧)无显著差异。

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Microvascular decompression in patients with hemifacial spasm.微血管减压术治疗面肌痉挛。
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