Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 236, Baidi Road, Nankai District, Tianjin, China.
Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 236, Baidi Road, Nankai District, Tianjin, China.
Ultrasound Med Biol. 2022 Sep;48(9):1941-1956. doi: 10.1016/j.ultrasmedbio.2022.05.032. Epub 2022 Jul 11.
Magneto-acoustic-electrical tomography (MAET) combines the advantages of ultrasound and electrical impedance functional tomography methods and has important research value in the early diagnosis of tumors and biocurrent monitoring. In this study, we propose a MAET method combining liquid metal image enhancement and maximum length sequence (MLS)-coded excitation to improve the signal-to-noise ratio (SNR) of MAET. The results indicate that liquid metal can achieve image enhancement of tissue MAET. When 7-, 15-, 31- and 63-bit MLS-coded excitations were applied to the samples, the SNR was improved by 28, 34, 40 and 45 dB, respectively. For a similar SNR improvement, the total used time under 31-bit MLS-coded excitation can be shortened to 23% under single-pulse excitation. The experimental results prove the feasibility of applying the MLS code to rotational MAET and reveal the significance of liquid metal as an image intensifier to improve the quality of MAET.
磁声电断层成像（MAET）结合了超声和电阻抗功能断层成像方法的优势，在肿瘤的早期诊断和生物电流监测方面具有重要的研究价值。本研究提出了一种结合液态金属图像增强和最大长度序列（MLS）编码激励的 MAET 方法，以提高 MAET 的信噪比（SNR）。结果表明，液态金属可以实现组织 MAET 的图像增强。当对样品施加 7、15、31 和 63 位 MLS 编码激励时，SNR 分别提高了 28、34、40 和 45 dB。对于类似的 SNR 提高，在单脉冲激励下，31 位 MLS 编码激励下的总用时可缩短至单脉冲激励下的 23%。实验结果证明了将 MLS 码应用于旋转 MAET 的可行性，并揭示了液态金属作为图像增强剂提高 MAET 质量的重要性。
