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In Vivo Electrical Conductivity Contrast Imaging in a Mouse Model of Cancer Using High-Frequency Magnetoacoustic Tomography With Magnetic Induction (hfMAT-MI).使用磁感应高频磁声断层扫描(hfMAT-MI)在癌症小鼠模型中进行体内电导率对比成像。
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Difference frequency magneto-acousto-electrical tomography (DF-MAET): application of ultrasound-induced radiation force to imaging electrical current density.差频磁声电成像(DF-MAET):超声致辐射力在成像电流密度中的应用。
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[磁声信号的编码激励处理方法研究]

[Research on coded excitation processing method for magneto-acoustic signal].

作者信息

Zhang Shunqi, Yin Tao, Liu Zhipeng

机构信息

Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, P.R.China.

Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192,

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2017 Oct 1;34(5):653-659. doi: 10.7507/1001-5515.201702042.

DOI:10.7507/1001-5515.201702042
PMID:29761949
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9935474/
Abstract

Detecting and imaging method of biological electrical characteristics based on magneto-acoustic coupling effect gives valuable information of tissue in early tumor diagnosis and bioelectrical current monitoring. Normal exciting and receiving method is to use single pulse. In this method the signal to noise ratio (SNR) is limited, so the imaging quality and imaging speed are low. In this study, we propose a processing method based on coded excitation to improve SNR and shorten the processing time. The processing method using 13 bit Barker coded excitation and 16 bit Golay code excitation are studied by simulation and experiments. The results show that SNR of magneto-acoustic signal is improved by 20.96 dB and 20.62 dB by using 13 bit Barker coded and 16 bit Golay coded excitation, respectively. It also indicates the processing time is short compare to single pulse mode. In the case of the SNR increasing, the overall acquiring and processing time under 13 bit Barker coded excitation and the 16 bit Golay coded excitation is shortened to 3.62% and 4.73%, respectively, compared to the single pulse excitation with waveform averaging method. In conclusion, the coded excitation will be significant for the improvement of magneto-acoustic signal SNR and imaging quality.

摘要

基于磁声耦合效应的生物电特性检测与成像方法在早期肿瘤诊断和生物电流监测中能提供有价值的组织信息。常规的激励和接收方法是使用单脉冲。在这种方法中,信噪比(SNR)受到限制,因此成像质量和成像速度较低。在本研究中,我们提出一种基于编码激励的处理方法来提高信噪比并缩短处理时间。通过仿真和实验研究了使用13位巴克码激励和16位格雷码激励的处理方法。结果表明,使用13位巴克码编码激励和16位格雷码编码激励时,磁声信号的信噪比分别提高了20.96 dB和20.62 dB。这也表明与单脉冲模式相比处理时间较短。在信噪比增加的情况下,与采用波形平均法的单脉冲激励相比,13位巴克码编码激励和16位格雷码编码激励下的总体采集和处理时间分别缩短至3.62%和4.73%。总之,编码激励对于提高磁声信号信噪比和成像质量具有重要意义。