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控制性 DCD 肺移植：规避想象和现实中的障碍——是否需要成立一个国际工作组？

Controlled DCD lung transplantation: Circumventing imagined and real barriers-time for an international taskforce?

机构信息

Division of Cardiothoracic Surgery, Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska.

Division of Cardiothoracic Surgery, Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska.

出版信息

J Heart Lung Transplant. 2022 Sep;41(9):1198-1203. doi: 10.1016/j.healun.2022.06.007. Epub 2022 Jun 13.

DOI:10.1016/j.healun.2022.06.007
PMID:35835677
Abstract

Controlled donation after circulatory death (DCD) has the potential to substantially increase the number of lung transplants thus offsetting some of the imbalance between need and organ availability. We examine the potential benefits associated with increased DCD utilization as well as the perceived barriers to the expansion of DCD. Solutions are offered as a means to expand DCD utilization across centers and nations.

摘要

控制性死后捐献（DCD）有可能大幅增加肺移植数量，从而在一定程度上缓解供需器官不匹配的问题。本文研究了增加 DCD 利用率所带来的潜在益处，以及扩大 DCD 利用所面临的公认障碍。本文提出了一些解决方案，旨在促进中心和国家之间扩大 DCD 的使用。

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引用本文的文献

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Cureus. 2025 Jul 2;17(7):e87196. doi: 10.7759/cureus.87196. eCollection 2025 Jul.
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Long-term outcomes of the international EXPAND trial of Organ Care System (OCS) Lung preservation for lung transplantation.器官护理系统（OCS）用于肺移植肺保存的国际EXPAND试验的长期结果。
EClinicalMedicine. 2025 Jul 8;85:103334. doi: 10.1016/j.eclinm.2025.103334. eCollection 2025 Jul.
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Surgeons are apprehensive to use DCD lungs despite similar post-transplant outcomes: A 20-year UNOS retrospective analysis.
尽管移植后结果相似，外科医生仍对使用心脏死亡后供体（DCD）肺脏心存顾虑：一项20年的器官共享联合网络（UNOS）回顾性分析。
JHLT Open. 2024 Nov 28;7:100185. doi: 10.1016/j.jhlto.2024.100185. eCollection 2025 Feb.
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JHLT Open. 2024 Feb 1;4:100058. doi: 10.1016/j.jhlto.2024.100058. eCollection 2024 May.
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