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卟啉病诱发的产后可逆性后部脑病综合征

Porphyria-induced Postpartum Reversible Posterior Encephalopathy Syndrome.

作者信息

Sharma Shri R, Sharma Nalini, Synmon Baiakmenlang, Hynniewtaya Yasmeen

机构信息

Shillong, Meghalaya, India.

Department of Neurology, NEIGRIHMS, Shillong, Meghalaya, India.

出版信息

Indian J Crit Care Med. 2022 Jun;26(6):728-730. doi: 10.5005/jp-journals-10071-24253.

DOI:10.5005/jp-journals-10071-24253
PMID:35836628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9237139/
Abstract

Acute intermittent porphyria (AIP) is a rare condition that needs to be kept in mind where its early recognition, conservative management, and removal of the precipitating factor are the key factors in its management. This "little imitator" presented with varied symptoms is often misdiagnosed. The diagnosis requires a strong index of suspicion as choosing an antiepileptic medication in the management of seizure requires a judicial choice to avoid precipitation of the underlying illness. Sharma SR, Sharma N, Synmon B, Hynniewtaya Y. Porphyria-induced Postpartum Reversible Posterior Encephalopathy Syndrome. Indian J Crit Care Med 2022;26(6):728-730.

摘要

急性间歇性卟啉病(AIP)是一种罕见疾病,在其管理中,早期识别、保守治疗以及消除诱发因素是关键,对此需要牢记于心。这种表现出多种症状的“小模仿者”常常被误诊。诊断需要高度怀疑指数,因为在癫痫管理中选择抗癫痫药物需要审慎抉择,以避免诱发潜在疾病。夏尔马SR、夏尔马N、辛蒙B、欣纽维塔亚Y。卟啉病诱发的产后可逆性后部脑病综合征。《印度重症监护医学杂志》2022年;26(6):728 - 730。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02b8/9237139/8565faf8982d/ijccm-26-728-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02b8/9237139/8565faf8982d/ijccm-26-728-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02b8/9237139/8565faf8982d/ijccm-26-728-g001.jpg

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本文引用的文献

1
Acute Intermittent Porphyria Presenting with Posterior Reversible Encephalopathy Syndrome: A Rare Cause of Abdominal Pain and Seizures.表现为后部可逆性脑病综合征的急性间歇性卟啉病:腹痛和癫痫发作的罕见病因
Indian J Crit Care Med. 2020 Aug;24(8):724-726. doi: 10.5005/jp-journals-10071-23532.
2
Porphyria-induced posterior reversible encephalopathy syndrome and central nervous system dysfunction.卟啉病相关性后部可逆性脑病综合征与中枢神经系统功能障碍。
Mol Genet Metab. 2019 Nov;128(3):242-253. doi: 10.1016/j.ymgme.2019.10.011. Epub 2019 Nov 1.
3
Acute intermittent porphyria presenting with seizures and posterior reversible encephalopathy syndrome: Two case reports and a literature review.
以癫痫发作和后部可逆性脑病综合征为表现的急性间歇性卟啉病:两例报告及文献综述
Medicine (Baltimore). 2018 Sep;97(36):e11665. doi: 10.1097/MD.0000000000011665.
4
Acute intermittent porphyria leading to posterior reversible encephalopathy syndrome (PRES): a rare cause of abdominal pain and seizures.急性间歇性卟啉症导致后部可逆性脑病综合征(PRES):腹痛和癫痫发作的罕见病因。
BMJ Case Rep. 2016 Jun 8;2016:bcr2016215350. doi: 10.1136/bcr-2016-215350.
5
Posterior reversible encephalopathy syndrome as a rare presenting feature of acute intermittent porphyria.后部可逆性脑病综合征作为急性间歇性卟啉病的一种罕见表现特征。
Neurol India. 2015 Jul-Aug;63(4):607-9. doi: 10.4103/0028-3886.162081.
6
Acute porphyrias in the USA: features of 108 subjects from porphyrias consortium.美国的急性卟啉病:来自卟啉病联盟的108名受试者的特征
Am J Med. 2014 Dec;127(12):1233-41. doi: 10.1016/j.amjmed.2014.06.036. Epub 2014 Jul 10.
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Intensive care management of patients with acute intermittent porphyria: Clinical report of four cases and review of literature.急性间歇性卟啉病患者的重症监护管理:4例临床报告及文献复习
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